Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   UXR76_RS06565 Genome accession   NZ_CP157306
Coordinates   1336498..1338507 (+) Length   669 a.a.
NCBI ID   WP_000516269.1    Uniprot ID   B1VK93
Organism   Staphylococcus aureus strain BSN85     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1331498..1343507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXR76_RS06550 (UXR76_006550) - 1332681..1333046 (+) 366 WP_000282386.1 RicAFT regulatory complex protein RicA family protein -
  UXR76_RS06555 (UXR76_006555) thiW 1333073..1333564 (+) 492 WP_000842277.1 energy coupling factor transporter S component ThiW -
  UXR76_RS06560 (UXR76_006560) hexA 1333867..1336485 (+) 2619 WP_000073352.1 DNA mismatch repair protein MutS Machinery gene
  UXR76_RS06565 (UXR76_006565) hexB 1336498..1338507 (+) 2010 WP_000516269.1 DNA mismatch repair endonuclease MutL Machinery gene
  UXR76_RS06570 (UXR76_006570) - 1338513..1339055 (+) 543 WP_001077635.1 glycerol-3-phosphate responsive antiterminator -
  UXR76_RS06575 (UXR76_006575) - 1339530..1340348 (+) 819 WP_001103743.1 MIP/aquaporin family protein -
  UXR76_RS06580 (UXR76_006580) glpK 1340477..1341973 (+) 1497 WP_000417372.1 glycerol kinase GlpK -

Sequence

Protein


Download         Length: 669 a.a.        Molecular weight: 76871.06 Da        Isoelectric Point: 5.0107

>NTDB_id=904550 UXR76_RS06565 WP_000516269.1 1336498..1338507(+) (hexB) [Staphylococcus aureus strain BSN85]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKNKVLYSFEQQKIEFEQRQNTENNQEKTFSSEESNSKSFMAENQNDEIVIKEDSYNPFV
TKTSESLITDDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNEDASVQNYENKASDDYYDVNDIKGTKSKDPKRRIPY
MEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIM
LEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREA
EDPFTCPHGRPIIINFSKYELEKLFKRVM

Nucleotide


Download         Length: 2010 bp        

>NTDB_id=904550 UXR76_RS06565 WP_000516269.1 1336498..1338507(+) (hexB) [Staphylococcus aureus strain BSN85]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAATAGAATGGCTATGAGCCATCCGGACATTCGAATAGC
ACTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGCTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATATCAATTGATAGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCAAAAAAAAATAAAGTATTATA
TTCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAG
AAAGTAACAGTAAGTCATTTATGGCAGAAAATCAAAACGATGAGATAGTTATAAAAGAAGATTCATATAATCCATTCGTA
ACGAAAACATCTGAAAGTTTAATAACTGATGATGAATCTTCTGGTTATAATAATACACGTGAAAAAGATGAAGACTACTT
CAAAAAACAACAAGAAATTTTACAAGAAATGGATCAAACATTTGATTCAAATGAGGATGCATCTGTGCAAAATTATGAGA
ATAAAGCGTCTGATGATTATTATGATGTAAACGATATTAAAGGAACAAAAAGTAAAGACCCTAAACGAAGAATTCCATAT
ATGGAAATTGTTGGCCAAGTACATGGGACGTATATTATTGCTCAAAATGAATTTGGCATGTACATGATTGACCAGCATGC
AGCTCAAGAAAGAATAAAATATGAATATTTTCGAGATAAAATAGGTGAAGTTACCAATGAAGTACAAGATTTATTAATCC
CGTTAACATTTCATTTTTCAAAGGATGAACAATTAGTTATTGATCAATATAAAAATGAGCTTCAACAAGTAGGTATCATG
TTAGAACATTTTGGTGGTCATGATTATATTGTAAGTAGCTATCCAGTTTGGTTCCCTAAAGATGAAGTAGAAGAAATCAT
TAAAGATATGATTGAGCTAATTTTGGAAGAGAAAAAAGTAGATATTAAAAAATTACGTGAAGATGTAGCAATCATGATGT
CATGTAAAAAATCTATTAAAGCGAATCATTATTTACAAAAACATGAAATGTCTGATTTAATTGATCAATTAAGAGAAGCG
GAAGATCCATTTACATGTCCACATGGTCGTCCAATAATCATTAATTTTTCAAAATACGAATTAGAAAAATTATTTAAGCG
TGTGATGTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(483-625)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B1VK93

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

40.828

100

0.413