Detailed information NTG0904320

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGW58_RS00455
• Genome accession: NZ_CP138666
• Coordinates: 82557..83600 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain DA70300
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 77557..88600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGW58_RS00425	-	78046..78156 (+)	111	WP_001790257.1	hypothetical protein	-
SGW58_RS00430	-	78185..78598 (+)	414	WP_001643743.1	hypothetical protein	-
SGW58_RS00435	-	78787..79773 (-)	987	WP_001014423.1	aromatic acid exporter family protein	-
SGW58_RS00440	map	80473..81231 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGW58_RS00445	-	81448..81844 (+)	397	Protein_88	hypothetical protein	-
SGW58_RS00450	liaF	81859..82560 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGW58_RS00455	vraS	82557..83600 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGW58_RS00460	vraR	83590..84219 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGW58_RS00465	-	84332..85549 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
SGW58_RS00470	-	85827..86102 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
SGW58_RS00475	-	86109..86573 (-)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
SGW58_RS00480	-	86720..86920 (+)	201	WP_000180460.1	DUF1128 family protein	-
SGW58_RS00485	-	86923..88179 (+)	1257	WP_001793983.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=904320 SGW58_RS00455 WP_001017131.1 82557..83600(+) (vraS) [Staphylococcus aureus strain DA70300]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=904320 SGW58_RS00455 WP_001017131.1 82557..83600(+) (vraS) [Staphylococcus aureus strain DA70300]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1