Detailed information NTG0904313

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGW61_RS09565
• Genome accession: NZ_CP138664
• Coordinates: 1937054..1938097 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain DA70504
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1932054..1943097

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGW61_RS09535	-	1932475..1933722 (-)	1248	WP_000656302.1	aminopeptidase	-
SGW61_RS09540	-	1933734..1933934 (-)	201	WP_338439047.1	DUF1128 family protein	-
SGW61_RS09545	-	1934081..1934545 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
SGW61_RS09550	-	1934552..1934827 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGW61_RS09555	-	1935105..1936322 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
SGW61_RS09560	vraR	1936435..1937064 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGW61_RS09565	vraS	1937054..1938097 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGW61_RS09570	liaF	1938094..1938795 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGW61_RS09575	-	1938810..1939196 (-)	387	WP_001110184.1	hypothetical protein	-
SGW61_RS09580	map	1939413..1940171 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
SGW61_RS09585	-	1940870..1941856 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SGW61_RS09590	-	1942034..1942447 (-)	414	WP_001622129.1	hypothetical protein	-
SGW61_RS09595	-	1942476..1942585 (-)	110	Protein_1852	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=904313 SGW61_RS09565 WP_001017131.1 1937054..1938097(-) (vraS) [Staphylococcus aureus strain DA70504]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=904313 SGW61_RS09565 WP_001017131.1 1937054..1938097(-) (vraS) [Staphylococcus aureus strain DA70504]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTGAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1