Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   L6423_RS04080 Genome accession   NZ_AP025204
Coordinates   793336..795189 (-) Length   617 a.a.
NCBI ID   WP_237014960.1    Uniprot ID   -
Organism   Helicobacter cinaedi strain 94105     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 788336..800189
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6423_RS04065 (Hc94105_0818) - 789672..790361 (-) 690 WP_104742652.1 response regulator -
  L6423_RS04070 (Hc94105_0819) - 790364..791848 (-) 1485 WP_237014875.1 HAMP domain-containing sensor histidine kinase -
  L6423_RS04075 (Hc94105_0820) - 791858..793339 (-) 1482 WP_237014876.1 hypothetical protein -
  L6423_RS04080 (Hc94105_0821) uvrC 793336..795189 (-) 1854 WP_237014960.1 excinuclease ABC subunit UvrC Machinery gene
  L6423_RS04085 (Hc94105_0822) - 795233..795691 (-) 459 WP_237014877.1 hypothetical protein -
  L6423_RS04090 (Hc94105_0823) - 795683..795931 (+) 249 WP_104742655.1 hypothetical protein -
  L6423_RS04095 (Hc94105_0824) nadB 795932..797377 (+) 1446 WP_237014878.1 L-aspartate oxidase -
  L6423_RS04100 (Hc94105_0825) - 797380..797577 (-) 198 WP_034584823.1 DUF5408 family protein -
  L6423_RS04105 (Hc94105_0826) - 797574..798452 (-) 879 WP_237014879.1 metal ABC transporter permease -
  L6423_RS04110 (Hc94105_0827) - 798383..799405 (-) 1023 WP_237014880.1 metal ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 71204.78 Da        Isoelectric Point: 9.7513

>NTDB_id=90429 L6423_RS04080 WP_237014960.1 793336..795189(-) (uvrC) [Helicobacter cinaedi strain 94105]
MYSLLFTLQNLPTQPGIYQYFDKDDNLLYVGKAKNLKNRIKSYFSIHNDIIAPKANLSQRIALMVSQVAKIHTLLTQTQE
DALILENSLIKSLKPKYNILLRDDKTYPYIYIDTSAAFPRFEITRKVLQSKHIEYFGPFVSGARELLDSLYDALPLVQKK
SCLKGKKACIFYQIHKCPAPCENKISQSQYAEYITQAKAFIDDRKGLIEILESKMQILSHNLQFEEAAKIRDRIQKLKTL
KTQSIIDIMSGDYDIFLLDSAGQNHILMMLFIRNGRIVSSDFSFIHQEIHSQNLASLYTQALLNHYKTPLPLPPKEILIP
YFDFQDKDEKDDLQKILQAQTQSHLKITQPQKGTKYNLLQLAKKNAQEILTLHTKEQNNAQNENATLYALKDLCNLSQVP
YRIEVFDTSHHSGSHNVGGMVVYENGEFIRNAYRRFELHSSDEYSQMSEMLTRRAKRFESNPPPDLWLLDGGKAQINLAL
DILKSVGANVDIIAIAKMKYGEKHNAKAYRSKGNALDILRTQNAEFKLSTNDKRLQFCQKLRDEVHRYAITYHRNKKQKD
IQKIQIQKGNNMDSSYSKAQIKRLLDYFGSFHAIQNAPKEQIENVLSRSFKSNKDSK

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=90429 L6423_RS04080 WP_237014960.1 793336..795189(-) (uvrC) [Helicobacter cinaedi strain 94105]
ATATATAGTTTGCTTTTCACCCTGCAAAATCTCCCCACACAGCCCGGAATCTACCAATATTTTGATAAAGATGATAATCT
ACTCTATGTCGGCAAGGCTAAAAATCTAAAAAATCGCATAAAAAGCTACTTTTCTATTCATAATGACATTATCGCGCCAA
AGGCTAATCTCAGCCAAAGAATAGCCCTTATGGTATCCCAAGTGGCTAAGATTCACACTTTGCTTACACAAACCCAAGAA
GATGCCCTTATCCTTGAAAACTCCCTTATCAAAAGCCTAAAGCCAAAGTATAATATTCTTTTGCGTGATGATAAAACTTA
TCCTTATATTTATATTGATACTTCTGCTGCTTTCCCACGATTTGAAATCACTCGCAAGGTGCTACAAAGTAAGCATATTG
AGTATTTTGGTCCTTTTGTGAGTGGGGCTAGAGAGCTACTTGATAGCCTTTATGACGCCCTGCCCCTTGTGCAGAAAAAG
TCCTGCCTTAAAGGCAAAAAGGCGTGTATATTTTATCAGATTCACAAATGCCCTGCCCCTTGTGAAAATAAAATCTCTCA
AAGTCAATATGCAGAATATATTACACAAGCAAAGGCGTTTATAGATGATAGAAAAGGGCTTATAGAGATTTTAGAATCTA
AAATGCAGATACTCTCACACAATCTACAATTTGAAGAGGCAGCAAAGATACGAGATAGAATCCAAAAGCTAAAAACACTA
AAAACCCAATCTATTATTGACATTATGAGCGGAGATTATGATATTTTTTTGCTTGATTCAGCAGGGCAAAATCATATCCT
TATGATGCTTTTTATCCGCAATGGACGCATTGTCTCAAGTGATTTTTCATTTATCCACCAAGAGATTCACAGCCAAAACC
TAGCCTCACTCTACACCCAAGCCTTACTTAATCACTATAAAACCCCTCTTCCCTTGCCACCAAAGGAGATTCTTATCCCA
TATTTTGACTTCCAAGACAAAGATGAAAAAGATGATTTGCAAAAGATTTTACAAGCCCAAACACAAAGTCATCTCAAAAT
CACCCAGCCACAAAAAGGCACAAAATATAACCTTTTGCAACTTGCTAAAAAGAACGCCCAAGAAATCCTAACTTTGCATA
CCAAAGAGCAAAATAATGCCCAAAATGAAAACGCCACTCTATACGCTCTAAAAGATTTATGCAATCTCTCTCAAGTGCCT
TATAGGATAGAGGTCTTTGACACCTCCCATCATAGCGGAAGCCATAATGTAGGCGGAATGGTAGTGTATGAAAATGGCGA
GTTTATCCGCAATGCTTACAGACGCTTTGAGCTTCATAGCAGTGATGAATACTCCCAAATGAGCGAAATGCTAACACGCA
GGGCAAAAAGATTTGAATCTAATCCGCCACCAGATTTATGGCTACTTGATGGCGGCAAAGCTCAAATCAACCTAGCACTT
GACATTCTAAAAAGTGTGGGGGCAAATGTGGATATTATCGCCATTGCCAAGATGAAATATGGGGAGAAGCACAATGCTAA
AGCTTATCGCTCTAAAGGCAATGCCCTTGATATTTTACGCACACAAAATGCGGAGTTTAAACTTAGCACAAACGATAAAA
GACTACAATTCTGTCAAAAGCTCCGCGATGAAGTGCATAGATATGCCATCACTTATCATCGCAATAAAAAACAAAAAGAC
ATACAAAAGATTCAGATTCAAAAAGGAAACAATATGGATAGCTCTTATAGCAAGGCTCAAATCAAGCGACTTTTAGATTA
TTTTGGCTCATTCCACGCCATTCAAAACGCTCCAAAAGAGCAGATAGAAAATGTGCTTTCACGCTCATTTAAAAGTAATA
AAGATTCAAAATGA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(207-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(392-550)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.575

98.703

0.499

Multiple sequence alignment