Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SGW65_RS12535 Genome accession   NZ_CP138661
Coordinates   2522178..2522852 (-) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain DA70870     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2505110..2522852 2522178..2522852 within 0
IScluster/Tn 2509012..2526604 2522178..2522852 within 0


Gene organization within MGE regions


Location: 2505110..2526604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGW65_RS12430 - 2505110..2505718 (+) 609 WP_000793183.1 hypothetical protein -
  SGW65_RS12435 - 2506193..2506285 (+) 93 WP_001791613.1 type I toxin-antitoxin system Fst family toxin -
  SGW65_RS12440 - 2506431..2507954 (+) 1524 WP_000837334.1 RNA-directed DNA polymerase -
  SGW65_RS12445 - 2508050..2508202 (+) 153 WP_000080034.1 hypothetical protein -
  SGW65_RS12450 - 2508583..2508951 (-) 369 Protein_2411 serine hydrolase -
  SGW65_RS12455 - 2509012..2509686 (-) 675 WP_001105987.1 IS6-like element IS257 family transposase -
  SGW65_RS12460 - 2509744..2510265 (+) 522 Protein_2413 replication initiation factor domain-containing protein -
  SGW65_RS12465 tet(K) 2510427..2511806 (+) 1380 WP_000492283.1 tetracycline efflux MFS transporter Tet(K) -
  SGW65_RS12470 mobV 2511993..2513192 (+) 1200 WP_001829561.1 MobV family relaxase -
  SGW65_RS12475 - 2513222..2513896 (+) 675 WP_001105960.1 IS6 family transposase -
  SGW65_RS12480 - 2514404..2515063 (-) 660 WP_000802831.1 RibD family protein -
  SGW65_RS12485 - 2515174..2515530 (-) 357 WP_000374054.1 WYL domain-containing protein -
  SGW65_RS12490 - 2515554..2516126 (-) 573 WP_001079938.1 HTH domain-containing protein -
  SGW65_RS12495 aph(3')-IIIa 2516402..2517196 (-) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  SGW65_RS12500 sat4 2517289..2517831 (-) 543 WP_000627290.1 streptothricin N-acetyltransferase Sat4 -
  SGW65_RS12505 - 2517828..2518463 (-) 636 Protein_2422 aminoglycoside 6-adenylyltransferase -
  SGW65_RS12510 - 2518604..2519278 (-) 675 WP_001105960.1 IS6 family transposase -
  SGW65_RS12515 - 2519335..2519511 (-) 177 Protein_2424 undecaprenyl-diphosphate phosphatase -
  SGW65_RS12520 - 2519525..2520262 (-) 738 WP_000369394.1 ABC transporter permease -
  SGW65_RS12525 - 2520255..2521184 (-) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  SGW65_RS12530 - 2521300..2522181 (-) 882 Protein_2427 sensor histidine kinase -
  SGW65_RS12535 braR 2522178..2522852 (-) 675 WP_000866106.1 response regulator transcription factor Regulator
  SGW65_RS12540 - 2522992..2523666 (-) 675 WP_001105960.1 IS6 family transposase -
  SGW65_RS12545 msr(A) 2524140..2525606 (+) 1467 WP_000438874.1 ABC-F type ribosomal protection protein Msr(A) -
  SGW65_RS12550 - 2525705..2526604 (+) 900 WP_000196697.1 Mph(C) family macrolide 2'-phosphotransferase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=904192 SGW65_RS12535 WP_000866106.1 2522178..2522852(-) (braR) [Staphylococcus aureus strain DA70870]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=904192 SGW65_RS12535 WP_000866106.1 2522178..2522852(-) (braR) [Staphylococcus aureus strain DA70870]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656