Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   SHT69_RS10125 Genome accession   NZ_CP138658
Coordinates   2097623..2099434 (-) Length   603 a.a.
NCBI ID   WP_319497093.1    Uniprot ID   -
Organism   Enterococcus faecalis strain ES-110-1     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2092623..2104434
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SHT69_RS10100 (SHT69_10100) - 2093448..2094245 (-) 798 WP_002356486.1 NAD kinase -
  SHT69_RS10105 (SHT69_10105) - 2094258..2094932 (-) 675 WP_002356484.1 GTP pyrophosphokinase family protein -
  SHT69_RS10110 (SHT69_10110) - 2095129..2095707 (+) 579 WP_002356483.1 CYTH domain-containing protein -
  SHT69_RS10115 (SHT69_10115) - 2095771..2096430 (+) 660 WP_002356482.1 ClpXP adapter SpxH family protein -
  SHT69_RS10120 (SHT69_10120) - 2096713..2097432 (-) 720 WP_002356481.1 helix-turn-helix transcriptional regulator -
  SHT69_RS10125 (SHT69_10125) pepF 2097623..2099434 (-) 1812 WP_319497093.1 oligoendopeptidase F Regulator
  SHT69_RS10130 (SHT69_10130) - 2099482..2100660 (-) 1179 WP_319497095.1 competence protein CoiA family protein -
  SHT69_RS10135 (SHT69_10135) - 2100750..2101412 (-) 663 WP_002356478.1 adaptor protein MecA -
  SHT69_RS10140 (SHT69_10140) spxA 2101755..2102153 (-) 399 WP_002356477.1 transcriptional regulator SpxA -
  SHT69_RS10145 (SHT69_10145) trpS 2102513..2103523 (+) 1011 WP_002359559.1 tryptophan--tRNA ligase -

Sequence

Protein


Download         Length: 603 a.a.        Molecular weight: 68865.15 Da        Isoelectric Point: 4.7145

>NTDB_id=904140 SHT69_RS10125 WP_319497093.1 2097623..2099434(-) (pepF) [Enterococcus faecalis strain ES-110-1]
MSEIKQLPTRDEVPTPLTWDLTKIFKDDAAFDVAYNQLTEELNQTESFKGTLGNGAEAFLAALEYVLDVYRKVETLYVYS
HLKNDQDTTNTAYQALYARASSLYAQVSEAVSWFDPEVLTLSDEQIWGYFEEQPKLAVYRHYIQNILDERPHVLSMEQEA
LLAGASEIFGASSNTFSILNNADLEFPTVQNAEGETIQLSHGVYGQLMESVDPSVREAAFKGLYKVYKQFRNTLASTLGA
HVKTHNYKAKIRNYDSARAASLASNHIPESVHETLVAVVNKHLPLLHRYVKLRKKLLNVEELHMYDLYAPLLGEAPIRYS
YEEAKEKAIEALKPLGEDYLSIVKEAFSSRWIDVIENQGKRSGAYSSGAYDTAPYILMNWHDSLDQLFTLVHEMGHSVHS
YYTRNNQPYVYGDYSIFLAEIASTTNENILTEYLLQTETDPKVRAYVLNHYLDGFKGTIFRQTQFAEFEHFIHTEDANGT
PLTSEYLSEYYGELNAKYYGPEVVRDEEISYEWARIPHFYYNYYVYQYATGFSAASALSKHILAGEEGALEKYLNYLKAG
SSDFPIEVMKKAGVDMTQAAYIEDAMKVFEERLTELEALVEKL

Nucleotide


Download         Length: 1812 bp        

>NTDB_id=904140 SHT69_RS10125 WP_319497093.1 2097623..2099434(-) (pepF) [Enterococcus faecalis strain ES-110-1]
ATGAGCGAAATTAAACAATTACCAACACGTGATGAAGTTCCAACTCCATTAACTTGGGATTTAACCAAAATTTTTAAAGA
TGATGCTGCTTTTGATGTTGCGTATAATCAGTTGACAGAAGAGCTAAATCAAACAGAATCATTTAAAGGAACCTTAGGGA
ATGGTGCAGAAGCTTTTCTAGCTGCGTTAGAATACGTTTTAGATGTCTATAGAAAAGTGGAAACATTATATGTCTATTCT
CATTTAAAAAATGATCAAGACACTACAAATACAGCTTACCAAGCTTTATATGCCAGAGCTAGTTCTTTATATGCACAAGT
TAGTGAAGCTGTTTCTTGGTTTGACCCAGAGGTTTTAACATTAAGTGATGAACAAATCTGGGGATATTTTGAAGAGCAGC
CGAAATTAGCTGTTTATCGTCACTATATTCAAAATATTTTAGATGAACGTCCCCATGTTTTATCGATGGAACAAGAAGCT
TTACTGGCGGGGGCTAGTGAAATTTTTGGTGCCTCAAGTAATACATTTTCAATTTTAAATAATGCAGACTTAGAATTTCC
AACTGTGCAAAATGCTGAAGGCGAAACGATTCAACTTTCTCATGGCGTTTATGGTCAATTAATGGAAAGTGTCGATCCAT
CTGTTCGTGAAGCAGCATTTAAAGGGTTGTACAAAGTGTACAAACAATTTAGAAATACATTAGCCTCAACTTTAGGTGCA
CATGTTAAAACGCATAATTATAAAGCAAAAATTAGAAATTATGATTCTGCTCGGGCAGCATCTTTAGCAAGTAATCATAT
CCCTGAAAGTGTTCACGAAACATTAGTAGCTGTAGTAAATAAACATTTACCTTTGCTACATCGTTATGTAAAATTAAGAA
AAAAATTATTAAACGTAGAAGAATTACACATGTACGACTTGTATGCGCCTTTGCTAGGTGAAGCACCAATTCGTTACAGC
TATGAAGAAGCAAAAGAAAAAGCAATTGAGGCTTTAAAACCACTAGGTGAAGACTATTTATCTATTGTTAAAGAAGCTTT
TTCAAGTCGTTGGATTGATGTGATTGAAAATCAAGGAAAACGAAGCGGCGCATATTCTTCAGGAGCTTATGATACAGCCC
CATACATTTTAATGAATTGGCATGATAGTTTGGATCAACTATTTACATTAGTCCATGAGATGGGCCATAGTGTTCATAGT
TACTATACAAGAAATAATCAGCCGTATGTTTATGGCGACTATTCAATTTTCTTAGCTGAGATTGCTTCAACCACAAATGA
AAATATTTTAACAGAATATTTATTACAAACAGAAACAGATCCTAAAGTACGTGCGTATGTCTTAAATCACTATTTAGACG
GCTTTAAGGGAACCATTTTCCGTCAAACCCAATTTGCGGAATTTGAACATTTTATTCACACGGAAGATGCTAATGGCACG
CCATTAACAAGTGAATATTTGAGTGAGTATTATGGCGAGCTCAATGCTAAATATTATGGACCAGAAGTAGTTAGAGACGA
AGAAATCAGTTACGAATGGGCGAGAATTCCACATTTTTATTACAATTACTATGTTTATCAATATGCAACTGGCTTCTCAG
CCGCTTCGGCATTGTCTAAACATATTTTAGCTGGAGAAGAAGGAGCTTTAGAGAAGTACCTTAACTACTTGAAAGCAGGA
AGTAGTGACTTCCCAATTGAAGTGATGAAAAAGGCGGGCGTGGATATGACACAAGCCGCGTATATCGAAGATGCAATGAA
AGTTTTTGAAGAACGTTTAACGGAATTAGAAGCTTTGGTTGAAAAATTATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(207-587)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

54.469

98.342

0.536