Detailed information NTG0903606

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGN29_RS09205
• Genome accession: NZ_CP138576
• Coordinates: 1902357..1903400 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain MFDS1022333
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1897357..1908400

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGN29_RS09175	-	1897779..1899035 (-)	1257	WP_001793428.1	aminopeptidase	-
SGN29_RS09180	-	1899038..1899238 (-)	201	WP_000180460.1	DUF1128 family protein	-
SGN29_RS09185	-	1899385..1899849 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SGN29_RS09190	-	1899856..1900131 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGN29_RS09195	-	1900409..1901626 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
SGN29_RS09200	vraR	1901738..1902367 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGN29_RS09205	vraS	1902357..1903400 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGN29_RS09210	liaF	1903397..1904098 (-)	702	WP_187395494.1	cell wall-active antibiotics response protein LiaF	-
SGN29_RS09215	-	1904113..1904499 (-)	387	WP_001110179.1	hypothetical protein	-
SGN29_RS09220	map	1904716..1905474 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGN29_RS09225	-	1906005..1906991 (+)	987	WP_000999716.1	aromatic acid exporter family protein	-
SGN29_RS09230	-	1907481..1907894 (-)	414	WP_001670387.1	hypothetical protein	-
SGN29_RS09235	-	1907923..1908033 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=903606 SGN29_RS09205 WP_001017131.1 1902357..1903400(-) (vraS) [Staphylococcus aureus strain MFDS1022333]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=903606 SGN29_RS09205 WP_001017131.1 1902357..1903400(-) (vraS) [Staphylococcus aureus strain MFDS1022333]
ATGAACCATTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1