Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | SAKRST72_RS00220 | Genome accession | NZ_CP138568 |
| Coordinates | 50678..52306 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186608.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain SAWL001 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 23966..72379 | 50678..52306 | within | 0 |
| SCCmec | 42353..58848 | 50678..52306 | within | 0 |
Gene organization within MGE regions
Location: 23966..72379
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SAKRST72_RS00100 (SAKRST72_00100) | yycF | 24424..25125 (+) | 702 | WP_000101976.1 | response regulator YycF | - |
| SAKRST72_RS00105 (SAKRST72_00105) | walK | 25138..26964 (+) | 1827 | WP_000871607.1 | cell wall metabolism sensor histidine kinase WalK | - |
| SAKRST72_RS00110 (SAKRST72_00110) | yycH | 26957..28291 (+) | 1335 | WP_001060140.1 | two-component system activity regulator YycH | - |
| SAKRST72_RS00115 (SAKRST72_00115) | yycI | 28292..29080 (+) | 789 | WP_001104168.1 | two-component system regulatory protein YycI | - |
| SAKRST72_RS00120 (SAKRST72_00120) | - | 29469..30269 (+) | 801 | WP_000088649.1 | MBL fold metallo-hydrolase | - |
| SAKRST72_RS00125 (SAKRST72_00125) | adsA | 30497..32815 (+) | 2319 | WP_000645771.1 | LPXTG-anchored adenosine synthase AdsA | - |
| SAKRST72_RS00130 (SAKRST72_00130) | rlmH | 33183..33662 (+) | 480 | WP_000704775.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| SAKRST72_RS00135 (SAKRST72_00135) | - | 33984..35240 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| SAKRST72_RS00140 (SAKRST72_00140) | - | 35655..35894 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| SAKRST72_RS00145 (SAKRST72_00145) | - | 35926..36600 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| SAKRST72_RS00150 (SAKRST72_00150) | - | 36691..37674 (-) | 984 | Protein_27 | protein rep | - |
| SAKRST72_RS00155 (SAKRST72_00155) | mobV | 37919..39181 (-) | 1263 | WP_029163598.1 | MobV family relaxase | - |
| SAKRST72_RS00160 (SAKRST72_00160) | bleO | 39688..40092 (-) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| SAKRST72_RS00165 (SAKRST72_00165) | aadD1 | 40309..41079 (-) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| SAKRST72_RS00170 (SAKRST72_00170) | - | 41272..41946 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| SAKRST72_RS00175 (SAKRST72_00175) | - | 42002..42307 (+) | 306 | Protein_32 | MaoC/PaaZ C-terminal domain-containing protein | - |
| SAKRST72_RS00180 (SAKRST72_00180) | mecA | 42353..44362 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| SAKRST72_RS00185 (SAKRST72_00185) | - | 44459..45445 (+) | 987 | WP_001549960.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SAKRST72_RS00190 (SAKRST72_00190) | - | 45417..45677 (+) | 261 | WP_001549961.1 | type I restriction enzyme endonuclease domain-containing protein | - |
| SAKRST72_RS00195 (SAKRST72_00195) | - | 45944..47143 (+) | 1200 | WP_073392450.1 | IS110-like element ISSep2 family transposase | - |
| SAKRST72_RS00200 (SAKRST72_00200) | - | 47240..48835 (-) | 1596 | Protein_37 | IS1182 family transposase | - |
| SAKRST72_RS00205 (SAKRST72_00205) | - | 48887..49393 (-) | 507 | WP_001092189.1 | DUF1643 domain-containing protein | - |
| SAKRST72_RS00210 (SAKRST72_00210) | - | 49408..49719 (-) | 312 | WP_000700851.1 | DUF960 family protein | - |
| SAKRST72_RS00215 (SAKRST72_00215) | - | 49806..50156 (-) | 351 | WP_000849672.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SAKRST72_RS00220 (SAKRST72_00220) | ccrB | 50678..52306 (-) | 1629 | WP_001186608.1 | recombinase family protein | Machinery gene |
| SAKRST72_RS00225 (SAKRST72_00225) | ccrA | 52328..53677 (-) | 1350 | WP_002486033.1 | recombinase family protein | Machinery gene |
| SAKRST72_RS00230 (SAKRST72_00230) | - | 53911..55704 (-) | 1794 | WP_000079474.1 | DUF927 domain-containing protein | - |
| SAKRST72_RS00235 (SAKRST72_00235) | - | 55704..56000 (-) | 297 | WP_000273823.1 | single-stranded DNA-binding protein | - |
| SAKRST72_RS00240 (SAKRST72_00240) | - | 56193..57239 (-) | 1047 | WP_001042023.1 | hypothetical protein | - |
| SAKRST72_RS00245 (SAKRST72_00245) | - | 57694..58848 (+) | 1155 | WP_000912116.1 | ATP-binding protein | - |
| SAKRST72_RS00250 (SAKRST72_00250) | - | 58878..59678 (+) | 801 | WP_000749913.1 | abortive infection family protein | - |
| SAKRST72_RS00255 (SAKRST72_00255) | - | 59861..60796 (+) | 936 | WP_000251226.1 | dsDNA nuclease domain-containing protein | - |
| SAKRST72_RS00260 (SAKRST72_00260) | - | 60789..61397 (+) | 609 | WP_029163516.1 | hypothetical protein | - |
| SAKRST72_RS00265 (SAKRST72_00265) | - | 61394..62461 (+) | 1068 | WP_223286853.1 | hypothetical protein | - |
| SAKRST72_RS00270 (SAKRST72_00270) | - | 62708..63694 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| SAKRST72_RS00275 (SAKRST72_00275) | - | 64003..64206 (+) | 204 | WP_000398680.1 | DUF6007 family protein | - |
| SAKRST72_RS00280 (SAKRST72_00280) | - | 64255..64551 (+) | 297 | WP_000179888.1 | TfoX/Sxy family protein | - |
| SAKRST72_RS00285 (SAKRST72_00285) | - | 64760..65362 (+) | 603 | WP_000908959.1 | hypothetical protein | - |
| SAKRST72_RS00290 (SAKRST72_00290) | - | 65654..66568 (-) | 915 | WP_000814441.1 | alpha/beta hydrolase | - |
| SAKRST72_RS00295 (SAKRST72_00295) | - | 66747..67301 (+) | 555 | WP_020977952.1 | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | - |
| SAKRST72_RS00300 (SAKRST72_00300) | - | 67531..68268 (+) | 738 | WP_001792407.1 | methyltransferase domain-containing protein | - |
| SAKRST72_RS00305 (SAKRST72_00305) | - | 68424..68906 (+) | 483 | WP_000410569.1 | hypothetical protein | - |
| SAKRST72_RS00310 (SAKRST72_00310) | - | 69112..70098 (+) | 987 | WP_000710561.1 | phosphatidylinositol-specific phospholipase C | - |
| SAKRST72_RS00315 (SAKRST72_00315) | - | 70319..71089 (+) | 771 | WP_000977794.1 | tandem-type lipoprotein | - |
| SAKRST72_RS00320 (SAKRST72_00320) | - | 71156..71923 (+) | 768 | WP_000649985.1 | tandem-type lipoprotein | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62654.83 Da Isoelectric Point: 9.7970
>NTDB_id=903507 SAKRST72_RS00220 WP_001186608.1 50678..52306(-) (ccrB) [Staphylococcus aureus strain SAWL001]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=903507 SAKRST72_RS00220 WP_001186608.1 50678..52306(-) (ccrB) [Staphylococcus aureus strain SAWL001]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTTCATGGTAAAGGAACGA
ATCTGCTTACAGGCATTATCCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACACTTAAAGAT
GGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTAATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTTCATGGTAAAGGAACGA
ATCTGCTTACAGGCATTATCCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACACTTAAAGAT
GGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTAATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
98.893 |
100 |
0.989 |