Detailed information NTG0090299

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: LPC25_RS13665
• Genome accession: NZ_AP025176
• Coordinates: 2731891..2732778 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain TPS5614
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2726891..2737778

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPC25_RS13635	-	2726909..2726997 (+)	89	Protein_2655	hypothetical protein	-
LPC25_RS13640 (TPS5614TP_25640)	-	2727105..2727602 (-)	498	WP_101244946.1	glutathione peroxidase	-
LPC25_RS13645 (TPS5614TP_25650)	-	2727612..2727872 (-)	261	WP_072434822.1	hypothetical protein	-
LPC25_RS13650	-	2728254..2728367 (-)	114	WP_072384844.1	hypothetical protein	-
LPC25_RS13655 (TPS5614TP_25660)	-	2729031..2731031 (-)	2001	WP_000776746.1	ABC transporter permease	-
LPC25_RS13660 (TPS5614TP_25670)	-	2731028..2731783 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
LPC25_RS13665 (TPS5614TP_25680)	braS	2731891..2732778 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
LPC25_RS13670 (TPS5614TP_25690)	braR	2732789..2733454 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
LPC25_RS13675 (TPS5614TP_25700)	-	2733480..2733680 (-)	201	WP_000604723.1	hypothetical protein	-
LPC25_RS13680 (TPS5614TP_25710)	-	2733878..2735227 (+)	1350	WP_000953732.1	alkaline phosphatase	-
LPC25_RS14205	-	2735287..2735388 (-)	102	WP_000731972.1	SE2200 family small protein	-
LPC25_RS13690 (TPS5614TP_25720)	-	2735510..2735965 (-)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
LPC25_RS13695 (TPS5614TP_25730)	-	2736211..2736972 (-)	762	WP_000323451.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=90299 LPC25_RS13665 WP_000143420.1 2731891..2732778(-) (braS) [Staphylococcus aureus strain TPS5614]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=90299 LPC25_RS13665 WP_000143420.1 2731891..2732778(-) (braS) [Staphylococcus aureus strain TPS5614]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993