Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   LPC25_RS07830 Genome accession   NZ_AP025176
Coordinates   1620175..1621149 (-) Length   324 a.a.
NCBI ID   WP_000697215.1    Uniprot ID   A0AAE8P9U4
Organism   Staphylococcus aureus strain TPS5614     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1615175..1626149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPC25_RS07790 (TPS5614TP_14930) gcvT 1615676..1616767 (-) 1092 WP_000093355.1 glycine cleavage system aminomethyltransferase GcvT -
  LPC25_RS07795 (TPS5614TP_14940) - 1616926..1617450 (-) 525 WP_001015122.1 shikimate kinase -
  LPC25_RS07800 - 1617440..1617586 (-) 147 WP_001789879.1 hypothetical protein -
  LPC25_RS07805 (TPS5614TP_14950) comGF 1617683..1618180 (-) 498 WP_029697681.1 competence type IV pilus minor pilin ComGF Machinery gene
  LPC25_RS07810 (TPS5614TP_14960) comGE 1618098..1618397 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  LPC25_RS07815 (TPS5614TP_14970) comGD 1618384..1618830 (-) 447 WP_075583651.1 competence type IV pilus minor pilin ComGD Machinery gene
  LPC25_RS07820 (TPS5614TP_14980) comGC 1618808..1619119 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  LPC25_RS07825 (TPS5614TP_14990) comGB 1619133..1620203 (-) 1071 WP_000776403.1 competence type IV pilus assembly protein ComGB Machinery gene
  LPC25_RS07830 (TPS5614TP_15000) comGA 1620175..1621149 (-) 975 WP_000697215.1 competence type IV pilus ATPase ComGA Machinery gene
  LPC25_RS07835 (TPS5614TP_15010) - 1621201..1621824 (-) 624 WP_001223006.1 MBL fold metallo-hydrolase -
  LPC25_RS07840 (TPS5614TP_15020) - 1621821..1622150 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  LPC25_RS07845 (TPS5614TP_15030) - 1622150..1623136 (-) 987 WP_000161315.1 ROK family glucokinase -
  LPC25_RS07850 (TPS5614TP_15040) - 1623133..1623336 (-) 204 WP_000087561.1 YqgQ family protein -
  LPC25_RS07855 (TPS5614TP_15050) - 1623317..1624780 (-) 1464 WP_001017872.1 rhomboid family protein -
  LPC25_RS07860 (TPS5614TP_15060) - 1624792..1625331 (-) 540 WP_000164551.1 5-formyltetrahydrofolate cyclo-ligase -
  LPC25_RS07865 (TPS5614TP_15070) rpmG 1625540..1625689 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36853.90 Da        Isoelectric Point: 8.8516

>NTDB_id=90282 LPC25_RS07830 WP_000697215.1 1620175..1621149(-) (comGA) [Staphylococcus aureus strain TPS5614]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNGIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGVSVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=90282 LPC25_RS07830 WP_000697215.1 1620175..1621149(-) (comGA) [Staphylococcus aureus strain TPS5614]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATGGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATTTATTTTTTGAGAATATCAACATTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAACAAGAAACAAGGATTACTATTGT
TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTTCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCCGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGTGTTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.383

100

0.994
  comGA Staphylococcus aureus N315

99.383

100

0.994

Multiple sequence alignment