Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ABH545_RS18350 Genome accession   NZ_CP157151
Coordinates   3357296..3357952 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain UTAK-6     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3352296..3362952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABH545_RS18310 (ABH545_18305) - 3352806..3353066 (+) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -
  ABH545_RS18315 (ABH545_18310) - 3353256..3353396 (+) 141 WP_000078920.1 Hok/Gef family protein -
  ABH545_RS18320 (ABH545_18315) - 3353586..3353867 (-) 282 WP_071529678.1 hypothetical protein -
  ABH545_RS18340 (ABH545_18335) pgsA 3354862..3355410 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ABH545_RS18345 (ABH545_18340) uvrC 3355467..3357299 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  ABH545_RS18350 (ABH545_18345) letA 3357296..3357952 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ABH545_RS18355 (ABH545_18350) - 3358094..3358165 (+) 72 Protein_3385 transcriptional regulator -
  ABH545_RS18360 (ABH545_18355) yecU 3358248..3358424 (+) 177 WP_000590347.1 protein YecU -
  ABH545_RS18365 (ABH545_18360) yecF 3358411..3358635 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ABH545_RS18370 (ABH545_18365) sdiA 3358702..3359425 (-) 724 Protein_3388 transcriptional regulator SdiA -
  ABH545_RS18375 (ABH545_18370) tcyN 3359655..3360407 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ABH545_RS18380 (ABH545_18375) tcyL 3360404..3361072 (-) 669 WP_001158206.1 cystine ABC transporter permease -
  ABH545_RS18385 (ABH545_18380) dcyD 3361087..3362073 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=902375 ABH545_RS18350 WP_000611335.1 3357296..3357952(-) (letA) [Escherichia coli strain UTAK-6]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=902375 ABH545_RS18350 WP_000611335.1 3357296..3357952(-) (letA) [Escherichia coli strain UTAK-6]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486