Detailed information NTG0902306

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SE858_RS06780
• Genome accession: NZ_CP138368
• Coordinates: 1313728..1314801 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain SagR92
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1308728..1319801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE858_RS06750 (SE858_06750)	-	1309621..1310685 (+)	1065	WP_000021302.1	MmcQ/YjbR family DNA-binding protein	-
SE858_RS06755 (SE858_06755)	asnA	1310799..1311791 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
SE858_RS06760 (SE858_06760)	-	1311836..1312285 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
SE858_RS06765 (SE858_06765)	rsmD	1312415..1312954 (+)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SE858_RS06770 (SE858_06770)	-	1312966..1313256 (+)	291	WP_000384889.1	hypothetical protein	-
SE858_RS06775 (SE858_06775)	coaD	1313253..1313738 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
SE858_RS06780 (SE858_06780)	sepM	1313728..1314801 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
SE858_RS06785 (SE858_06785)	-	1314876..1316208 (+)	1333	Protein_1260	bifunctional metallophosphatase/5'-nucleotidase	-
SE858_RS06790 (SE858_06790)	-	1316277..1316855 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
SE858_RS06795 (SE858_06795)	rlmN	1316906..1318012 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SE858_RS06800 (SE858_06800)	-	1318012..1318527 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=902306 SE858_RS06780 WP_000796095.1 1313728..1314801(+) (sepM) [Streptococcus agalactiae strain SagR92]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=902306 SE858_RS06780 WP_000796095.1 1313728..1314801(+) (sepM) [Streptococcus agalactiae strain SagR92]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658