Detailed information NTG0902217

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SE117_RS09465
• Genome accession: NZ_CP138363
• Coordinates: 1943401..1944444 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 15V8707
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1938401..1949444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE117_RS09435 (SE117_09435)	-	1938822..1940078 (-)	1257	WP_001793428.1	aminopeptidase	-
SE117_RS09440 (SE117_09440)	-	1940081..1940281 (-)	201	WP_000180462.1	DUF1128 family protein	-
SE117_RS09445 (SE117_09445)	-	1940428..1940892 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SE117_RS09450 (SE117_09450)	-	1940899..1941174 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SE117_RS09455 (SE117_09455)	-	1941452..1942669 (+)	1218	WP_000037094.1	YihY/virulence factor BrkB family protein	-
SE117_RS09460 (SE117_09460)	vraR	1942782..1943411 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
SE117_RS09465 (SE117_09465)	vraS	1943401..1944444 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SE117_RS09470 (SE117_09470)	liaF	1944441..1945142 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SE117_RS09475 (SE117_09475)	-	1945157..1945543 (-)	387	WP_001110180.1	hypothetical protein	-
SE117_RS09480 (SE117_09480)	map	1945760..1946518 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SE117_RS09485 (SE117_09485)	-	1947090..1948076 (+)	987	WP_000999713.1	FUSC family protein	-
SE117_RS09490 (SE117_09490)	-	1948265..1948678 (-)	414	WP_014532664.1	hypothetical protein	-
SE117_RS09495 (SE117_09495)	-	1948707..1948819 (-)	113	Protein_1833	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=902217 SE117_RS09465 WP_001017131.1 1943401..1944444(-) (vraS) [Staphylococcus aureus strain 15V8707]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=902217 SE117_RS09465 WP_001017131.1 1943401..1944444(-) (vraS) [Staphylococcus aureus strain 15V8707]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1