Detailed information NTG0902174

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SE116_RS09320
• Genome accession: NZ_CP138362
• Coordinates: 1927450..1928493 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain V315
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1922450..1933493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE116_RS09290 (SE116_09290)	-	1922871..1924127 (-)	1257	WP_001793428.1	aminopeptidase	-
SE116_RS09295 (SE116_09295)	-	1924130..1924330 (-)	201	WP_000180462.1	DUF1128 family protein	-
SE116_RS09300 (SE116_09300)	-	1924477..1924941 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SE116_RS09305 (SE116_09305)	-	1924948..1925223 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SE116_RS09310 (SE116_09310)	-	1925501..1926718 (+)	1218	WP_000037094.1	YihY/virulence factor BrkB family protein	-
SE116_RS09315 (SE116_09315)	vraR	1926831..1927460 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
SE116_RS09320 (SE116_09320)	vraS	1927450..1928493 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SE116_RS09325 (SE116_09325)	liaF	1928490..1929191 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SE116_RS09330 (SE116_09330)	-	1929206..1929592 (-)	387	WP_001110180.1	hypothetical protein	-
SE116_RS09335 (SE116_09335)	map	1929809..1930567 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SE116_RS09340 (SE116_09340)	-	1931082..1932068 (+)	987	WP_000999713.1	FUSC family protein	-
SE116_RS09345 (SE116_09345)	-	1932257..1932670 (-)	414	WP_014532664.1	hypothetical protein	-
SE116_RS09350 (SE116_09350)	-	1932699..1932785 (-)	87	WP_319162667.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=902174 SE116_RS09320 WP_001017131.1 1927450..1928493(-) (vraS) [Staphylococcus aureus strain V315]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=902174 SE116_RS09320 WP_001017131.1 1927450..1928493(-) (vraS) [Staphylococcus aureus strain V315]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1