Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SE087_RS10605 Genome accession   NZ_CP138360
Coordinates   2120837..2121553 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 17CS1042     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2115837..2126553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SE087_RS10575 (SE087_10575) - 2116052..2116678 (+) 627 WP_000522384.1 nitroreductase family protein -
  SE087_RS10580 (SE087_10580) - 2117040..2117825 (+) 786 WP_217175948.1 carbon-nitrogen family hydrolase -
  SE087_RS10585 (SE087_10585) hld 2118424..2118504 (-) 81 WP_000046022.1 delta-hemolysin -
  SE087_RS10590 (SE087_10590) agrB 2118795..2119364 (+) 570 WP_001105714.1 accessory gene regulator AgrB -
  SE087_RS10595 (SE087_10595) agrD 2119361..2119501 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  SE087_RS10600 (SE087_10600) agrC 2119526..2120818 (+) 1293 WP_319085296.1 quorum-sensing sensor histidine kinase AgrC -
  SE087_RS10605 (SE087_10605) agrA 2120837..2121553 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  SE087_RS10610 (SE087_10610) - 2121625..2121738 (+) 114 WP_115289669.1 hypothetical protein -
  SE087_RS10615 (SE087_10615) - 2121926..2122885 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  SE087_RS10620 (SE087_10620) - 2122882..2124366 (-) 1485 WP_319085352.1 sucrose-6-phosphate hydrolase -
  SE087_RS10625 (SE087_10625) - 2124516..2125466 (-) 951 WP_217175945.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=902134 SE087_RS10605 WP_000688492.1 2120837..2121553(+) (agrA) [Staphylococcus aureus strain 17CS1042]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=902134 SE087_RS10605 WP_000688492.1 2120837..2121553(+) (agrA) [Staphylococcus aureus strain 17CS1042]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCC
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1