Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   SE146_RS01425 Genome accession   NZ_CP138339
Coordinates   279447..281666 (+) Length   739 a.a.
NCBI ID   WP_020997305.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain TH2288     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 274447..286666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SE146_RS01415 (SE146_01410) - 274463..279061 (-) 4599 WP_050169346.1 S6 family peptidase -
  SE146_RS01420 (SE146_01415) - 279140..279415 (-) 276 WP_153707850.1 hypothetical protein -
  SE146_RS01425 (SE146_01420) comA 279447..281666 (+) 2220 WP_020997305.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SE146_RS01430 (SE146_01425) comL 281736..282539 (-) 804 WP_003687645.1 outer membrane protein assembly factor BamD Machinery gene
  SE146_RS01435 (SE146_01430) rluD 282538..283662 (+) 1125 WP_003687642.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  SE146_RS01440 (SE146_01435) - 283815..284762 (-) 948 Protein_279 bile acid:sodium symporter family protein -
  SE146_RS01445 - 284839..285063 (-) 225 WP_226876112.1 hypothetical protein -
  SE146_RS01450 (SE146_01440) pgeF 285215..285994 (+) 780 WP_003687651.1 peptidoglycan editing factor PgeF -
  SE146_RS01455 (SE146_01445) lptE 286046..286525 (+) 480 WP_003687653.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 739 a.a.        Molecular weight: 79820.60 Da        Isoelectric Point: 10.3677

>NTDB_id=901909 SE146_RS01425 WP_020997305.1 279447..281666(+) (comA) [Neisseria gonorrhoeae strain TH2288]
MFRRWFLPCWVVGVAVSFALSVVPHWPFWLAAFAVLAVLARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWRAEAVSGVP
LTVEVTDMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGVGGV
GTVGADRVLLHGGSGWGIAVWRSRISRNWRQADADGGLSDGIGLMRALSVGEQSALRPGLWQAFRPLGLTHLVSISGLHV
TMVAVLFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPLAVLGVGTWLSFGLVAALIWACAGRLYEGKRQTAVRGQWAASVLSLVLLGYLFASLPLVSPLVNAVSIPWFSW
VLTPLALLGSVVPFAPLQQAGAFLAEYTLRFLVWLADVSPEFAVAAAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVSYRPEAVPENEAAVTVWDAGQGLSVLVRTANRHLLFDTGTVAAAQTGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLRPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEESLVG
KYGGNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRVYKFYWQKKPFE

Nucleotide


Download         Length: 2220 bp        

>NTDB_id=901909 SE146_RS01425 WP_020997305.1 279447..281666(+) (comA) [Neisseria gonorrhoeae strain TH2288]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGCGTGGCAGTTTCGTTCGCACTGTCGGTTGTACCGCATTGGCC
GTTTTGGTTGGCGGCTTTTGCGGTTTTGGCTGTGCTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGAACGGAAGCGGCACTGTCTTCGCAATGGCGGGCGGAGGCGGTTTCAGGCGTGCCT
TTGACGGTGGAAGTGACGGATATGCCGAGGTCGGACGGGCGGCGCGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGCGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGCG
TGCACCCCGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGGGTAGGCGGCGTG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
CAATTGGCGGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGGATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATTTCGGGTTTGCACGTT
ACGATGGTGGCGGTGCTGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCCGCCCGGCCGCGCGC
GTGGGTTTTGGCGGCGGGGTGTGCGGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGTG
TTTTGATGTTGGCGGCGTTCGCGTGGGCGTGGCGCAGGGGAAGACTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCTTTGGCGGTTTTGGGTGTCGGTACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGTGCAGGGCGTTTGTACGAGGGGAAACGGCAAACCGCCGTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCTCTGG
TTTTGCTCGGTTATCTGTTTGCCTCGCTGCCTTTGGTCAGCCCTTTGGTCAATGCGGTGTCGATACCGTGGTTTTCTTGG
GTGTTGACCCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCGCTTCAGCAGGCGGGGGCATTTTTGGCGGAATA
CACTTTGCGGTTTTTGGTGTGGCTTGCCGATGTGTCGCCTGAGTTTGCCGTTGCCGCCGCACCTTTGCCGCTGCTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTATCCTACCGTCCTGAAGCAGTACCTGAAAACGAAGCTGCGGTTACGGTTTGGGATGCGGGGCAGGGCTTGTCGGT
GCTTGTGCGGACGGCAAACCGCCATCTGCTTTTCGATACGGGAACGGTAGCGGCGGCACAAACGGGTATCGTGCCGAGTT
TGAATGCGGCGGGTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGCTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCCGGACAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTCGAGTTTTTGAGGCCGTCTGAACGCAAAAATATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCGGGCGGTGCGGCACTGCTGGTAACGGGAGATTTGGATACGAAGGGCGAGGAAAGCCTGGTCGGC
AAGTATGGAGGCAACCTGTACAGCCAGGTGTTGGTGTTGGGGCATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCT
CAATGCCGTTTCGCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAGCATCCGACCGAAGCGGTGCAGA
ACCGTGTCCGCGCACACGGCATCAAGTTGTTGCGGACGGATTTGTCGGGCGCGCTGCAATTCGGCTTGGGACGCGGAGGC
GTAAAGGCTCAACGTTTGAGAGTGTATAAATTCTATTGGCAGAAAAAACCGTTTGAGTGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(208-465)

Metallo-beta-lactamase superfamily (Lactamase_B)

(500-677)

Domain of unknown function (DUF4131) (DUF4131)

(7-167)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

100

100

1