Detailed information NTG0901733

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SC043_RS11425
• Genome accession: NZ_CP138309
• Coordinates: 2243626..2244654 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis strain B26
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2238626..2249654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SC043_RS11400 (SC043_11400)	-	2238912..2239409 (-)	498	WP_021214977.1	nitroreductase family protein	-
SC043_RS11405 (SC043_11405)	-	2239396..2239605 (-)	210	WP_003132661.1	hypothetical protein	-
SC043_RS11410 (SC043_11410)	-	2239602..2240429 (-)	828	WP_010906344.1	radical SAM protein	-
SC043_RS11415 (SC043_11415)	-	2240422..2242545 (-)	2124	WP_010906345.1	radical SAM protein	-
SC043_RS11420 (SC043_11420)	-	2242648..2243505 (-)	858	WP_010906346.1	transcriptional regulator	-
SC043_RS11425 (SC043_11425)	sepM	2243626..2244654 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
SC043_RS11430 (SC043_11430)	coaD	2244641..2245138 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
SC043_RS11435 (SC043_11435)	rsmD	2245186..2245725 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SC043_RS11440 (SC043_11440)	-	2245896..2247116 (-)	1221	WP_023349137.1	MFS transporter	-
SC043_RS11445 (SC043_11445)	lmrP	2247200..2248426 (-)	1227	WP_021214981.1	multidrug efflux MFS transporter LmrP	-
SC043_RS11450 (SC043_11450)	-	2248614..2249108 (+)	495	WP_010906351.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=901733 SC043_RS11425 WP_010906347.1 2243626..2244654(-) (sepM) [Lactococcus lactis strain B26]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=901733 SC043_RS11425 WP_010906347.1 2243626..2244654(-) (sepM) [Lactococcus lactis strain B26]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491