Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   R6U80_RS12090 Genome accession   NZ_CP137623
Coordinates   2433093..2434121 (-) Length   342 a.a.
NCBI ID   WP_098397363.1    Uniprot ID   -
Organism   Lactococcus lactis strain NCK401     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2428093..2439121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6U80_RS12070 (R6U80_12070) - 2429168..2430025 (-) 858 WP_058203259.1 Rgg/GadR/MutR family transcriptional regulator -
  R6U80_RS12075 (R6U80_12075) - 2430136..2431275 (-) 1140 WP_313791887.1 MFS transporter -
  R6U80_RS12080 (R6U80_12080) kwcM 2431272..2432591 (-) 1320 WP_058220852.1 KxxxW cyclic peptide radical SAM maturase -
  R6U80_RS12085 (R6U80_12085) - 2432659..2432772 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  R6U80_RS12090 (R6U80_12090) sepM 2433093..2434121 (-) 1029 WP_098397363.1 SepM family pheromone-processing serine protease Regulator
  R6U80_RS12095 (R6U80_12095) coaD 2434108..2434605 (-) 498 WP_010906348.1 pantetheine-phosphate adenylyltransferase -
  R6U80_RS12100 (R6U80_12100) rsmD 2434653..2435192 (-) 540 WP_015427191.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R6U80_RS12105 (R6U80_12105) - 2435363..2436583 (-) 1221 WP_098397364.1 MFS transporter -
  R6U80_RS12110 (R6U80_12110) lmrP 2436667..2437893 (-) 1227 WP_012898648.1 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37350.90 Da        Isoelectric Point: 9.8070

>NTDB_id=899427 R6U80_RS12090 WP_098397363.1 2433093..2434121(-) (sepM) [Lactococcus lactis strain NCK401]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGEDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=899427 R6U80_RS12090 WP_098397363.1 2433093..2434121(-) (sepM) [Lactococcus lactis strain NCK401]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTTCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGCGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAGAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.986

100

0.494