Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   R6U80_RS09730 Genome accession   NZ_CP137623
Coordinates   1998318..1999019 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain NCK401     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1993318..2004019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6U80_RS09710 (R6U80_09710) - 1993428..1994645 (-) 1218 WP_058223190.1 cysteine desulfurase -
  R6U80_RS09715 (R6U80_09715) sufD 1994645..1995901 (-) 1257 WP_021722250.1 Fe-S cluster assembly protein SufD -
  R6U80_RS09720 (R6U80_09720) sufC 1996039..1996809 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  R6U80_RS09725 (R6U80_09725) - 1996984..1998315 (-) 1332 WP_021722251.1 glycosyltransferase family 4 protein -
  R6U80_RS09730 (R6U80_09730) mecA 1998318..1999019 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  R6U80_RS09735 (R6U80_09735) - 1999149..1999883 (-) 735 WP_004255171.1 amino acid ABC transporter ATP-binding protein -
  R6U80_RS09740 (R6U80_09740) - 1999883..2000569 (-) 687 WP_004255158.1 amino acid ABC transporter permease -
  R6U80_RS09745 (R6U80_09745) - 2000716..2001624 (-) 909 WP_058223188.1 diacylglycerol kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=899409 R6U80_RS09730 WP_004255173.1 1998318..1999019(-) (mecA) [Lactococcus lactis strain NCK401]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=899409 R6U80_RS09730 WP_004255173.1 1998318..1999019(-) (mecA) [Lactococcus lactis strain NCK401]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97