Detailed information NTG0899390

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: R6U80_RS02950
• Genome accession: NZ_CP137623
• Coordinates: 574646..577096 (+)
• Length: 816 a.a.
• NCBI ID: WP_313791816.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain NCK401
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 569646..582096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6U80_RS02925 (R6U80_02925)	-	570410..570922 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
R6U80_RS02930 (R6U80_02930)	rpoE	571139..571702 (+)	564	WP_012897344.1	DNA-directed RNA polymerase subunit delta	-
R6U80_RS02935 (R6U80_02935)	mltG	571839..573491 (+)	1653	WP_058220628.1	endolytic transglycosylase MltG	-
R6U80_RS02940 (R6U80_02940)	greA	573551..574024 (+)	474	WP_033899645.1	transcription elongation factor GreA	-
R6U80_RS02945 (R6U80_02945)	-	574201..574656 (+)	456	WP_010905471.1	CtsR family transcriptional regulator	-
R6U80_RS02950 (R6U80_02950)	clpC	574646..577096 (+)	2451	WP_313791816.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
R6U80_RS02955 (R6U80_02955)	hpf	577231..577788 (+)	558	WP_003129564.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
R6U80_RS02960 (R6U80_02960)	eno	577973..579274 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
R6U80_RS02965 (R6U80_02965)	-	579362..580297 (+)	936	WP_165379818.1	tyrosine-type recombinase/integrase	-
R6U80_RS02970 (R6U80_02970)	-	580682..580921 (+)	240	WP_098394067.1	hypothetical protein	-
R6U80_RS02975 (R6U80_02975)	-	580952..581110 (+)	159	WP_179884634.1	hypothetical protein	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90394.75 Da
• Isoelectric Point: 6.4340

>NTDB_id=899390 R6U80_RS02950 WP_313791816.1 574646..577096(+) (clpC) [Lactococcus lactis strain NCK401]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMDVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKVAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEALAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=899390 R6U80_RS02950 WP_313791816.1 574646..577096(+) (clpC) [Lactococcus lactis strain NCK401]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTAGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGGATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACCTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGTAAGGTGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGCTTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACATAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTTGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• AAA lid domain (AAA_lid_9) (357-453)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.632	100	0.996
clpC	Streptococcus thermophilus LMD-9	50.421	100	0.513
clpC	Streptococcus thermophilus LMG 18311	50.301	100	0.512
clpC	Streptococcus pneumoniae Rx1	49.216	100	0.5
clpC	Streptococcus pneumoniae D39	49.216	100	0.5
clpC	Streptococcus pneumoniae TIGR4	49.095	100	0.499
clpC	Streptococcus mutans UA159	48.558	100	0.495
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	98.284	0.495
clpE	Streptococcus mutans UA159	47.692	79.657	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	46.87	80.27	0.376
clpE	Streptococcus pneumoniae TIGR4	47.528	76.838	0.365
clpE	Streptococcus pneumoniae Rx1	47.528	76.838	0.365
clpE	Streptococcus pneumoniae D39	47.528	76.838	0.365
clpE	Streptococcus pneumoniae R6	47.528	76.838	0.365