Detailed information NTG0899389

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: R6U80_RS02475
• Genome accession: NZ_CP137623
• Coordinates: 483772..486018 (+)
• Length: 748 a.a.
• NCBI ID: WP_313791823.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain NCK401
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 478772..491018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6U80_RS02455 (R6U80_02455)	rpoD	479366..480709 (+)	1344	WP_003130829.1	RNA polymerase sigma factor RpoD	-
R6U80_RS02460 (R6U80_02460)	-	480824..481567 (+)	744	WP_058221077.1	MurR/RpiR family transcriptional regulator	-
R6U80_RS02465 (R6U80_02465)	-	481732..483099 (+)	1368	WP_313791825.1	MFS transporter	-
R6U80_RS02470 (R6U80_02470)	-	483383..483721 (+)	339	WP_313791824.1	hypothetical protein	-
R6U80_RS02475 (R6U80_02475)	clpC	483772..486018 (+)	2247	WP_313791823.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
R6U80_RS02480 (R6U80_02480)	-	486306..486776 (-)	471	WP_003130820.1	Rrf2 family transcriptional regulator	-
R6U80_RS02485 (R6U80_02485)	gap	486949..487962 (+)	1014	WP_003130818.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
R6U80_RS02490 (R6U80_02490)	def	488105..488740 (-)	636	WP_003130816.1	peptide deformylase	-
R6U80_RS02495 (R6U80_02495)	-	488888..489349 (+)	462	WP_308858979.1	RNA pyrophosphohydrolase	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83125.82 Da
• Isoelectric Point: 4.7618

>NTDB_id=899389 R6U80_RS02475 WP_313791823.1 483772..486018(+) (clpC) [Lactococcus lactis strain NCK401]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALHGQDFNGAAST
QTPPTQTGGRGPHGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAETKKNEATQAEDFEKAAHFRDQITKLRELQNHEVS
DDEIPVITEKDIEQIVEQKTHIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKIAKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKELV
ADLIDDKIVISNQAQETAETTDEEVPAE

Nucleotide

• Length: 2247 bp

>NTDB_id=899389 R6U80_RS02475 WP_313791823.1 483772..486018(+) (clpC) [Lactococcus lactis strain NCK401]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGCGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAACGGAA
ATTCTGATGAACCATTTAATCCATTTAATGATATCTTTAGTGCTTTGCACGGTCAAGATTTTAATGGAGCAGCAAGCACT
CAAACTCCACCAACACAAACAGGTGGACGTGGTCCGCACGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGAATGTT
AGAAGAATTTGGAATTAACATCACAGAGTCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATTA
AACGTGTCATTGAGATTTTAAATCGTAGGACTAAGAATAATCCTGTATTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCGCAAAAAATTGTGGACGGAGATGTGCCGCAAAAACTACAAAATAAAGAAGTGATTCGTCTTGA
TGTTGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTGATTATGTTTATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCTGCCGGTGATGGCAATATGGAT
GCAGGAAATATCCTAAAACCTGCGCTTGCGCGTGGTGAGCTTCAATTGGTCGGAGCAACAACGCTCAATGAATATCGCAT
CATTGAAAAAGATGCTGCGCTTGAACGCCGGATGCAACCAGTTAAAGTCGATGAACCATCAGTTGATGAAACAATTACTA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCACGTGAAATACACTGATGAGGCTATTGAAGCAGCCGCTCAT
TTGTCAAATCGTTACATTCAAGACCGTTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGTCTGGTTCTAAGAAAAA
TCTAACCTTGAAATTTGTTGATCCTGAAGATATTAATCGTCGGATTGCGGATGCAGAAACGAAGAAAAATGAAGCAACAC
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCACTAAACTTCGTGAATTACAAAATCATGAAGTTTCA
GATGATGAAATTCCTGTCATCACTGAAAAAGATATTGAACAAATTGTTGAGCAAAAAACACATATTCCAGTTGGTGATTT
GAAAGAAAAAGAACAAACCCAATTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAGGATGAAGCAGTGG
ATAAGATTGCTAAAGCTATCCGTCGTTCTCGTGTGGGACTTGGTAAACCTAATCGTCCAATTGGTTCTTTCCTTTTCGTT
GGTCCAACAGGTGTTGGTAAAACAGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAAAGTATGATTCG
TTTTGACATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGAGCCCCTCCAGGATATGTGGGTTATGAAG
AAGCTGGTCAATTGACTGAACGTGTTCGTCGTAATCCCTACAGTTTGATTTTATTAGATGAAATCGAAAAAGCACATCCA
GATGTGATGCACATGTTCTTGCAAATTCTTGAAGATGGACGTCTGACAGACGCACAAGGACGGACAGTATCCTTTAAAGA
TAGTTTGATTATTATGACTTCTAATGCCGGAACTGGTAAAGTTGAAGCCTCTGTCGGATTTGGTGCTGCTCGTGAGGGAC
GAACTAAATCAGTGCTTGGTCAGCTTGGCGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATAATTGAATTC
TCTGCTTTGAGCAAAGAAAATCTCCTTAAAATTGTTGATTTGATGCTTGATGAAGTCAACGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCAGCAAAAGAAAAATTAGTTGATTTAGGTTACAATCCAGCAATGGGTGCTAGACCAC
TTCGTAGAACAATTCAAGAAAATATCGAAGATTCAATTGCTGACTTCTATATTGAACACCCTGAATACAAAGAATTGGTT
GCTGATTTGATTGATGATAAAATTGTTATCTCTAATCAAGCTCAAGAAACAGCAGAAACGACTGATGAAGAAGTTCCTGC
TGAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (287-386)

• ATPase family associated with various cellular activities (AAA) (AAA) (149-268)

• AAA domain (Cdc48 subfamily) (AAA_2) (472-635)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (643-713)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	97.861	100	0.979
clpE	Streptococcus mutans UA159	76.026	100	0.767
clpE	Streptococcus pneumoniae Rx1	75.543	98.396	0.743
clpE	Streptococcus pneumoniae D39	75.543	98.396	0.743
clpE	Streptococcus pneumoniae R6	75.543	98.396	0.743
clpE	Streptococcus pneumoniae TIGR4	75.543	98.396	0.743
clpC	Bacillus subtilis subsp. subtilis str. 168	51.672	87.968	0.455
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.635	81.952	0.39
clpC	Streptococcus pneumoniae Rx1	46.635	83.422	0.389
clpC	Streptococcus pneumoniae D39	46.635	83.422	0.389
clpC	Streptococcus pneumoniae TIGR4	46.635	83.422	0.389
clpC	Streptococcus thermophilus LMD-9	46.104	82.353	0.38
clpC	Streptococcus thermophilus LMG 18311	45.942	82.353	0.378
clpC	Streptococcus mutans UA159	45.631	82.62	0.377