Detailed information NTG0898916

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: R5Y33_RS09745
• Genome accession: NZ_CP137531
• Coordinates: 1970573..1971766 (+)
• Length: 397 a.a.
• NCBI ID: WP_002216225.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain EXNM741
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1965573..1976766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R5Y33_RS09730	-	1966496..1967095 (+)	600	WP_002216221.1	DUF4390 domain-containing protein	-
R5Y33_RS09735	-	1967095..1969212 (+)	2118	WP_002247928.1	PAS domain-containing sensor histidine kinase	-
R5Y33_RS09740	-	1969205..1970482 (+)	1278	WP_002247929.1	sigma-54 dependent transcriptional regulator	-
R5Y33_RS09745	dprA	1970573..1971766 (+)	1194	WP_002216225.1	DNA-processing protein DprA	Machinery gene
R5Y33_RS09750	-	1971792..1972253 (+)	462	WP_002215351.1	DUF494 family protein	-
R5Y33_RS09755	topA	1972325..1974631 (+)	2307	WP_002224383.1	type I DNA topoisomerase	-
R5Y33_RS09760	-	1974704..1975399 (-)	696	WP_002216227.1	hypothetical protein	-
R5Y33_RS09765	-	1976090..1976467 (+)	378	WP_002247931.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 42654.87 Da
• Isoelectric Point: 6.3983

>NTDB_id=898916 R5Y33_RS09745 WP_002216225.1 1970573..1971766(+) (dprA) [Neisseria meningitidis strain EXNM741]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVALAVRHKQAAEAWRNAEKRASARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPSNKNLAYEIAERGLIVSEFPLDTRPFAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPRLLQNEGASSYSINKGMPEKRITAVQT
ASDQLSLPEGKMPSEKTENRPVGGSILDRMGFDPVHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1194 bp

>NTDB_id=898916 R5Y33_RS09745 WP_002216225.1 1970573..1971766(+) (dprA) [Neisseria meningitidis strain EXNM741]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCTGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCCTCGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCCGTCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCGTTGCAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCTTATGAAATTGCCGAAAGGGGATTGATTGTCAGCGAGTTCCCTTTGGACACGCGTCCGTTTG
CAGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCACTGTCGCAAGTAACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGTTTGGCGGCAGAAATGGGGCGCGAGGTAATGGCGGTACCCGGTTCGATAGACAACCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGCCTGGACGACATCCTGAACGAATGCCCGC
GGCTCTTGCAAAATGAGGGTGCTTCGTCATATTCTATAAATAAGGGAATGCCTGAAAAGCGCATCACTGCCGTTCAGACG
GCATCCGACCAGCTGTCTCTGCCTGAAGGCAAAATGCCGTCTGAAAAGACGGAGAACCGACCCGTCGGCGGCAGTATCTT
GGACAGGATGGGTTTCGACCCAGTTCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCG
CACTGTTGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterProScan.

• DprA winged helix domain (DprA_WH) (344-390)

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	94.962	100	0.95
dprA	Neisseria meningitidis MC58	94.962	100	0.95
dprA	Neisseria gonorrhoeae strain FA1090	89.421	100	0.894
dprA	Neisseria gonorrhoeae MS11	89.169	100	0.892
dprA	Vibrio cholerae strain A1552	37.845	100	0.38
dprA	Vibrio campbellii strain DS40M4	36.99	98.741	0.365