Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   R5Y34_RS09065 Genome accession   NZ_CP137530
Coordinates   1811956..1812651 (-) Length   231 a.a.
NCBI ID   WP_002215704.1    Uniprot ID   Q7DDR6
Organism   Neisseria meningitidis strain EXNM678     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1796548..1813481 1811956..1812651 within 0


Gene organization within MGE regions


Location: 1796548..1813481
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R5Y34_RS08985 - 1797980..1798225 (-) 246 WP_002226028.1 hypothetical protein -
  R5Y34_RS08990 - 1798337..1798765 (+) 429 WP_002226027.1 CopD family protein -
  R5Y34_RS08995 - 1798777..1799253 (+) 477 WP_002226026.1 CYTH domain-containing protein -
  R5Y34_RS09000 - 1799603..1800091 (-) 489 WP_002235430.1 dihydrofolate reductase -
  R5Y34_RS09005 aroG 1800159..1801214 (-) 1056 WP_002235429.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  R5Y34_RS09010 - 1801376..1801603 (-) 228 WP_153310284.1 hypothetical protein -
  R5Y34_RS09015 - 1801881..1802138 (+) 258 WP_002231679.1 membrane protein -
  R5Y34_RS09020 - 1802187..1802291 (-) 105 Protein_1750 IS1595 family transposase -
  R5Y34_RS09025 comE 1802966..1803430 (-) 465 WP_025463168.1 ComEA family DNA-binding protein Machinery gene
  R5Y34_RS09055 - 1809229..1810035 (-) 807 WP_002221447.1 inner membrane protein YpjD -
  R5Y34_RS09060 ffh 1810255..1811625 (+) 1371 WP_002221448.1 signal recognition particle protein -
  R5Y34_RS09065 dsbA2 1811956..1812651 (-) 696 WP_002215704.1 DsbA family protein Machinery gene
  R5Y34_RS09070 - 1812822..1813481 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25419.90 Da        Isoelectric Point: 5.1502

>NTDB_id=898863 R5Y34_RS09065 WP_002215704.1 1811956..1812651(-) (dsbA2) [Neisseria meningitidis strain EXNM678]
MKLKTLALTSLTLLALAACSKQAETSVPADSAQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=898863 R5Y34_RS09065 WP_002215704.1 1811956..1812651(-) (dsbA2) [Neisseria meningitidis strain EXNM678]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGTGT
TCCGGCAGACAGCGCCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCTGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(65-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7DDR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

100

100

1
  dsbA1 Neisseria meningitidis MC58

71.245

100

0.719