Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   OHP008_RS03240 Genome accession   NZ_AP024965
Coordinates   684159..685943 (-) Length   594 a.a.
NCBI ID   WP_223888673.1    Uniprot ID   -
Organism   Helicobacter pylori strain #8     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 679159..690943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHP008_RS03210 (OHP008_06470) - 679613..679861 (+) 249 WP_212865713.1 RNA-binding protein -
  OHP008_RS03215 (OHP008_06480) - 680059..680880 (-) 822 WP_212866795.1 glycosyltransferase family 25 protein -
  OHP008_RS03220 (OHP008_06490) trxB 681188..682123 (-) 936 WP_223888672.1 thioredoxin-disulfide reductase -
  OHP008_RS03225 (OHP008_06500) trxA 682129..682449 (-) 321 WP_033587185.1 thioredoxin -
  OHP008_RS03230 (OHP008_06510) - 682538..682882 (-) 345 WP_212869802.1 YraN family protein -
  OHP008_RS03235 (OHP008_06520) - 682883..684148 (-) 1266 WP_212782202.1 homoserine dehydrogenase -
  OHP008_RS03240 (OHP008_06530) uvrC 684159..685943 (-) 1785 WP_223888673.1 excinuclease ABC subunit UvrC Machinery gene
  OHP008_RS03245 (OHP008_06540) - 685944..686405 (-) 462 WP_000437184.1 hypothetical protein -
  OHP008_RS03250 - 686397..686576 (+) 180 WP_000468796.1 hypothetical protein -
  OHP008_RS03255 (OHP008_06550) - 686588..687229 (-) 642 WP_212861779.1 ABC transporter ATP-binding protein -
  OHP008_RS03260 (OHP008_06560) - 687231..688814 (-) 1584 WP_406943787.1 ABC transporter permease/substrate-binding protein -
  OHP008_RS03265 (OHP008_06570) - 688929..689366 (-) 438 WP_001875641.1 hypothetical protein -
  OHP008_RS03270 (OHP008_06580) motB 689372..690145 (-) 774 WP_223888674.1 flagellar motor protein MotB -
  OHP008_RS03275 (OHP008_06590) motA 690148..690921 (-) 774 WP_000366185.1 flagellar motor stator protein MotA -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68756.97 Da        Isoelectric Point: 9.5297

>NTDB_id=89759 OHP008_RS03240 WP_223888673.1 684159..685943(-) (uvrC) [Helicobacter pylori strain #8]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMEHLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYAQMSELLSRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEEASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=89759 OHP008_RS03240 WP_223888673.1 684159..685943(-) (uvrC) [Helicobacter pylori strain #8]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAATCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCATCGCGCTAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCATTGGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAGGAGCTTGAATTAA
AAATGGAGCACCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAAATCTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCCCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACGCTCAAATGAGCGAATTACTCAGCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTTCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAGAAGCGAGCGAACAGGAAAAAAA
TGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97

Multiple sequence alignment