Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LDM85_RS04480 Genome accession   NZ_AP024963
Coordinates   931956..933740 (+) Length   594 a.a.
NCBI ID   WP_223887250.1    Uniprot ID   -
Organism   Helicobacter pylori strain #5     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 926956..938740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDM85_RS04445 (OHP005_09150) motA 927026..927799 (+) 774 WP_000366185.1 flagellar motor stator protein MotA -
  LDM85_RS04450 (OHP005_09160) motB 927802..928569 (+) 768 WP_223887247.1 flagellar motor protein MotB -
  LDM85_RS04455 (OHP005_09170) - 928573..929010 (+) 438 WP_001031792.1 hypothetical protein -
  LDM85_RS04460 (OHP005_09180) - 929110..930666 (+) 1557 WP_223887248.1 ABC transporter permease/substrate-binding protein -
  LDM85_RS04465 (OHP005_09190) - 930670..931311 (+) 642 WP_223887249.1 ATP-binding cassette domain-containing protein -
  LDM85_RS04470 - 931323..931502 (-) 180 WP_000468796.1 hypothetical protein -
  LDM85_RS04475 (OHP005_09200) - 931494..931955 (+) 462 WP_000437186.1 hypothetical protein -
  LDM85_RS04480 (OHP005_09210) uvrC 931956..933740 (+) 1785 WP_223887250.1 excinuclease ABC subunit UvrC Machinery gene
  LDM85_RS04485 (OHP005_09220) - 933751..935016 (+) 1266 WP_223887251.1 homoserine dehydrogenase -
  LDM85_RS04490 (OHP005_09230) - 935017..935361 (+) 345 WP_223887252.1 YraN family protein -
  LDM85_RS04495 (OHP005_09240) trxA 935450..935770 (+) 321 WP_000020200.1 thioredoxin -
  LDM85_RS04500 (OHP005_09250) trxB 935776..936711 (+) 936 WP_223887253.1 thioredoxin-disulfide reductase -
  LDM85_RS04505 (OHP005_09260) - 936878..937690 (+) 813 WP_212889555.1 glycosyltransferase family 25 protein -
  LDM85_RS04510 (OHP005_09270) - 937885..938133 (-) 249 WP_000790556.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68850.18 Da        Isoelectric Point: 9.6675

>NTDB_id=89713 LDM85_RS04480 WP_223887250.1 931956..933740(+) (uvrC) [Helicobacter pylori strain #5]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFKLECMPYRVEIFDV
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=89713 LDM85_RS04480 WP_223887250.1 931956..933740(+) (uvrC) [Helicobacter pylori strain #5]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTATCCACAATAATGAAATCACGCCCA
ATCATCGTACAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTGAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGACAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCTATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCCCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTCGCCAAAGAAC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTACTCCCTAGCGACAAACGCTTACAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.306

100

0.973

Multiple sequence alignment