Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   ABC811_RS00950 Genome accession   NZ_CP155535
Coordinates   173867..176698 (+) Length   943 a.a.
NCBI ID   WP_363748868.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PJ755/1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 168867..181698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC811_RS00925 (ABC811_00925) - 169432..169995 (+) 564 WP_000166585.1 DNA-3-methyladenine glycosylase I -
  ABC811_RS00930 (ABC811_00930) - 169992..170669 (+) 678 WP_000987423.1 type II CAAX endopeptidase family protein -
  ABC811_RS00935 (ABC811_00935) - 170810..171841 (-) 1032 WP_000255087.1 S66 peptidase family protein -
  ABC811_RS00940 (ABC811_00940) - 172096..172779 (-) 684 WP_000078026.1 DUF1129 domain-containing protein -
  ABC811_RS00945 (ABC811_00945) - 172791..173735 (-) 945 WP_000815629.1 magnesium transporter CorA family protein -
  ABC811_RS00950 (ABC811_00950) uvrA 173867..176698 (+) 2832 WP_363748868.1 excinuclease ABC subunit UvrA Machinery gene
  ABC811_RS00955 (ABC811_00955) - 176691..177752 (+) 1062 WP_001042886.1 Xaa-Pro peptidase family protein -
  ABC811_RS00960 (ABC811_00960) - 177829..178782 (-) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -
  ABC811_RS00965 (ABC811_00965) spx 179130..179528 (+) 399 WP_000591165.1 transcriptional regulator Spx -
  ABC811_RS00970 (ABC811_00970) - 179594..180163 (+) 570 WP_000725141.1 SP0191 family lipoprotein -
  ABC811_RS00975 (ABC811_00975) - 180250..180516 (+) 267 WP_000507059.1 IreB family regulatory phosphoprotein -
  ABC811_RS00980 (ABC811_00980) ruvX 180520..180939 (+) 420 WP_033630867.1 Holliday junction resolvase RuvX -
  ABC811_RS00985 (ABC811_00985) - 180955..181260 (+) 306 WP_000017620.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 943 a.a.        Molecular weight: 104160.35 Da        Isoelectric Point: 6.5413

>NTDB_id=897008 ABC811_RS00950 WP_363748868.1 173867..176698(+) (uvrA) [Streptococcus pneumoniae strain PJ755/1]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDN
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNML
EQAMTAFGVAMDKPFEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYM
NELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNLQNVTARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGIRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

Nucleotide


Download         Length: 2832 bp        

>NTDB_id=897008 ABC811_RS00950 WP_363748868.1 173867..176698(+) (uvrA) [Streptococcus pneumoniae strain PJ755/1]
ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCGCGAGACAAGTT
GGTTGTCGTGACTGGCTTGTCAGGTTCAGGGAAGTCCAGTTTGGCTTTTGATACCCTCTATGCGGAGGGACAACGTCGCT
ATGTAGAGAGTTTGTCCGCCTACGCTCGTCAGTTCTTGGGAAATATGGAAAAACCAGATGTAGATGCCATTGATGGTCTC
AGCCCAGCTATTTCTATCGACCAGAAAACGACTAGCAAAAACCCTCGCTCGACGGTGGGAACAACGACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCGCGTGTGGGGACGCCTTACTGTATCAACGGGCATGGGGCTATCAAGGCTTCTTCTGTGG
AGCAAATCGTTGATAAGGTTTTGGAGTTACCTGAACGCCAGCGCTTGCAGATCTTGTCTCCTGTCATCCGCAAGAAAAAA
GGCCAACATAAGAGTGTTATCGAGAAGGTTCAGAAAGACGGGTATGTTCGTGTCCGTGTGGATGGGGAAGTCTATGATGT
GACCGAAGTGCCAGAGTTGTCTAAGAGCAAGCAACACAATATCGATGTCGTGGTTGACCGTATTGTTATCAAGGAGGGCA
TTCGTAGTCGTCTCTTTGATTCCATTGAGGCTGCCCTTCGTATTGCAGAAGGTTATGTCATTATCGACACCATGGACAAC
TCTGAGTTGTTGTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGTTTTACTGTCCCAGAGTTAGAGCCTCGTCTCTTTTC
TTTCAATGCTCCTTTTGGCTCTTGTAGTGAGTGTGACGGCTTGGGCATCAAGCTGGAGGTGGATACTGATTTGGTAGTGC
CAAATGCCAGCAAAACCTTACATGAGGGAGCGCTGGCACCTTGGAATCCTATCTCATCCAACTACTATCCAAACATGCTA
GAGCAGGCCATGACGGCTTTTGGAGTGGCTATGGATAAGCCTTTTGAGGACTTGTCAGAAGAAGACAAGAACTTGATTCT
CTACGGCTCAGATGGTAAGAAATTCCATTTCCACTATGAGAATGAATTTGGTGGCGTGCGCGATATCGACATTCCGTTTG
AGGGAGTTATCAATAATATCAAACGTCGTTACCATGAAACCAATAGCGATTACACTCGCACTCAGATGCGCCTCTACATG
AATGAGCTGACTTGCGGAACCTGTCACGGTTATCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGTGGTGAGCAAGG
GCCACATATCGGAGAAATTTCAGACCTGTCTATCGCAGATCACTTGGACTTGGTGAGCCAGTTAACTTTGTCTGAAAATG
AAGCCATCATTGCTCGTCCCATTCTCAAGGAAATCAAGGATCGTTTGACCTTCCTTAATAATGTGGGTCTTAACTATCTA
ACCCTGTCACGTTCAGCAGGAACCCTTTCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCAACCCAGATTGGTTCCAACCT
ATCAGGCGTCCTCTATATCCTAGACGAGCCGTCAATCGGTCTTCACCAGAGAGACAATGACCGCCTGATTGCCAGTCTGA
AAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACACGACGAAGATACCATGCGTGAAGCTGATTATCTGATT
GACGTTGGTCCTGGTGCCGGTGTTTTTGGTGGTGAGATTGTTGCAGCAGGTACACCTAAGCAAGTGGCTCGCAACAGCAA
GTCTATCACAGGTCAGTACTTGTCAGGCAAACGTGTCATCCCAGTACCAGAAGAGCGCCGTGTCGGAAATGGTCGTTTTA
TTGAAGTGATAGGAGCGCGTGAGAACAACTTGCAAAATGTCACGGCTCGCTTTCCACTAGGAAAATTTATCGCAGTGACA
GGTGTGTCGGGTTCAGGGAAATCGACTCTAATCAACAGCATTCTCAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTC
AGACAAACCTGGTAAGTTTAAGACTATTACAGGGATTGAGCATGTCGACCGTTTGATTGATATTGACCAGAGCCCTATCG
GACGGACGCCGAGGTCTAACCCAGCTACCTATACAGGAGTTTTTGACGATATACGTGACCTTTTTGCTCAGACAAATGAA
GCCAAGATTCGAGGCTACAAGAAGGGACGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGTGAAGCTTGCTCAGGTGACGG
GATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTATGTGGCTTGTGAAGTTTGCCACGGAATCCGCTATAACAGTG
AAACCCTAGAAGTTCACTACAAGGAAAAGAATATTTCGCAGGTCTTGGATATGACGGTCAACGATGCGGTAGAATTTTTC
CAACACATTCCGAAAATTCAACGCAAACTCCAGACCATCAAGGATGTAGGGCTAGGCTATGTGACCTTGGGACAGCCAGC
TACCACCCTTTCTGGGGGAGAAGCCCAACGTATGAAGTTAGCTAGCGAACTCCACAAACGCTCGACAGGAAAATCTTTCT
ACATTCTGGATGAACCGACGACAGGGCTTCATACAGAGGACATTGCTCGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGAC
GATGGCAATACAGTCCTCGTCATCGAGCACAATCTGGATGTTATCAAGACGGCAGACCATATCATTGACTTGGGACCTGA
GGGCGGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAACGAAGCCAGCTATACAGGAC
ACTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(132-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)

ABC transporter (ABC_tran)

(624-860)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

98.834

100

0.988
  uvrA Streptococcus pneumoniae TIGR4

98.834

100

0.988
  uvrA Streptococcus pneumoniae D39

98.834

100

0.988