Detailed information NTG0896746

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: ABC810_RS10170
• Genome accession: NZ_CP155532
• Coordinates: 2011384..2014215 (-)
• Length: 943 a.a.
• NCBI ID: WP_001152894.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SP264
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2006384..2019215

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC810_RS10135 (ABC810_10140)	-	2006560..2007810 (-)	1251	WP_000464336.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
ABC810_RS10140 (ABC810_10145)	-	2008068..2008373 (-)	306	WP_000017620.1	DUF1292 domain-containing protein	-
ABC810_RS10145 (ABC810_10150)	ruvX	2008389..2008808 (-)	420	WP_001808830.1	Holliday junction resolvase RuvX	-
ABC810_RS10150 (ABC810_10155)	-	2008812..2009078 (-)	267	WP_000507059.1	IreB family regulatory phosphoprotein	-
ABC810_RS10155 (ABC810_10160)	-	2009165..2009734 (-)	570	WP_000725133.1	SP0191 family lipoprotein	-
ABC810_RS10160 (ABC810_10165)	spx	2009800..2010198 (-)	399	WP_000591165.1	transcriptional regulator Spx	-
ABC810_RS10165 (ABC810_10170)	-	2010330..2011391 (-)	1062	WP_001042860.1	Xaa-Pro peptidase family protein	-
ABC810_RS10170 (ABC810_10175)	uvrA	2011384..2014215 (-)	2832	WP_001152894.1	excinuclease ABC subunit UvrA	Machinery gene
ABC810_RS10175 (ABC810_10180)	-	2014347..2015291 (+)	945	WP_000815629.1	magnesium transporter CorA family protein	-
ABC810_RS10180 (ABC810_10185)	-	2015303..2015986 (+)	684	WP_000078027.1	DUF1129 domain-containing protein	-
ABC810_RS10185 (ABC810_10190)	-	2016241..2017272 (+)	1032	WP_000255102.1	S66 peptidase family protein	-
ABC810_RS10190 (ABC810_10195)	-	2017409..2018086 (-)	678	WP_000987429.1	type II CAAX endopeptidase family protein	-
ABC810_RS10195 (ABC810_10200)	-	2018083..2018646 (-)	564	WP_000166600.1	DNA-3-methyladenine glycosylase I	-

Sequence

Protein

• Length: 943 a.a.
• Molecular weight: 104110.20 Da
• Isoelectric Point: 6.3902

>NTDB_id=896746 ABC810_RS10170 WP_001152894.1 2011384..2014215(-) (uvrA) [Streptococcus pneumoniae strain SP264]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDD
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNML
EQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYM
NELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNLQNVTARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
AGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

Nucleotide

• Length: 2832 bp

>NTDB_id=896746 ABC810_RS10170 WP_001152894.1 2011384..2014215(-) (uvrA) [Streptococcus pneumoniae strain SP264]
ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCGCGAGACAAGTT
GGTTGTCGTGACTGGCTTGTCAGGTTCAGGGAAGTCCAGTCTGGCTTTTGATACTCTCTATGCGGAGGGACAACGTCGCT
ATGTAGAGAGTTTGTCTGCCTACGCTCGTCAGTTCTTGGGAAATATGGAAAAACCAGATGTAGATGCCATTGATGGTCTC
AGCCCAGCTATTTCCATCGACCAGAAAACGACTAGTAAAAATCCTCGCTCGACGGTGGGAACGACGACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCACGTGTGGGGACGCCTTACTGTATCAACGGACATGGAGCTATCAATGCTTCTTCTGTGG
AGCAAATCGTTGATAAGGTTTTGGAGTTACCTGAACGCCAGCGCTTGCAGATCTTGGCTCCTGTCATCCGCAAGAAAAAA
GGCCAACATAAGAGTGTTATCGAGAAGGTTCAGAAAGACGGGTATGTTCGTGTTCGTGTGGATGGGGAAGTCTATGATGT
GACCGAAGTGCCAGAGTTGTCTAAGAGCAAGCAACACAATATCGATGTCGTGGTTGACCGTATTGTTATCAAGGAGGGCA
TTCGTAGCCGTCTCTTTGATTCCATTGAAGCTGCCCTTCGTATCGCAGAAGGTTATGTGATTATCGACACCATGGACGAC
TCTGAGTTGTTGTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGATTTACTGTCCCAGAGTTAGAACCTCGTCTCTTCTC
TTTCAATGCTCCCTTTGGCTCTTGTAGTGAGTGTGACGGCTTGGGGATTAAGCTGGAGGTGGATACTGATTTGGTAGTGC
CAGATGCCAGCAAAACCTTACATGAGGGAGCGCTGGCACCTTGGAATCCTATCTCATCCAACTACTATCCAAACATGTTA
GAGCAGGCCATGAAAGTCTTTGGAGTGGCTATGGATAAGCCTTTTGAGGACCTGTCAGAAGAAGATAAGAACTTGATTCT
CTACGGCTCAGATGGTAAGGAATTCCATTTCCATTATGAAAATGAATTTGGTGGTGTGCGCGATATCGACATTCCGTTTG
AGGGAGTTATCAATAATATCAAACGTCGTTACCATGAAACCAATAGCGATTACACTCGCACTCAGATGCGTCTCTACATG
AATGAGCTGACCTGCGGAACCTGTCAAGGCTATCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGCGGCCAGCAAGG
GCCACATATTGGAGAAATCTCAGACCTGTCTATCGCTGACCACTTGGACTTGGTGAGCCAGTTAACTTTGTCTGAAAATG
AAGCCATCATTGCTCGTCCCATTCTCAAGGAAATCAAGGATCGTTTGACCTTCCTTAATAATGTGGGTCTTAACTATCTA
ACCCTGTCACGTTCAGCAGGAACCCTTTCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCAACCCAGATTGGTTCCAACCT
ATCAGGTGTCCTCTATATCCTAGACGAGCCGTCAATCGGTCTTCACCAGAGGGACAATGACCGCCTGATTGCCAGTCTGA
AAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACACGACGAAGATACCATGCGTGAAGCTGATTATCTGATT
GACGTTGGTCCTGGTGCCGGTGTTTTTGGTGGTGAGATTGTTGCAGCAGGTACACCTAAGCAAGTGGCTCGCAACAGCAA
GTCTATCACAGGTCAGTACTTGTCAGGCAAACGTGTCATCCCAGTACCAGAAGAGCGCCGTGTCGGAAATGGTCGTTTTA
TTGAAGTGACAGGAGCGCGTGAGAACAACTTGCAAAATGTCACGGCTCGCTTTCCACTAGGAAAATTTATCGCAGTGACA
GGTGTGTCGGGTTCAGGGAAATCGACTCTAATCAACAGCATTCTCAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTC
AGACAAACCTGGTAAGTTTAAGACTATTACAGGGATTGAGCATGTCGACCGTTTGATTGATATTGACCAGAGCCCTATCG
GACGGACGCCGAGGTCTAACCCAGCTACCTATACAGGAGTTTTTGACGATATACGTGACCTTTTTGCTCAGACAAATGAA
GCCAAGATTCGAGGCTACAAGAAGGGGCGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGTGAAGCTTGCTCAGGTGACGG
GATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTATGTGGCTTGTGAAGTTTGCCACGGAACCCGCTATAACAGTG
AAACCCTAGAAGTTCACTACAAGGAAAAGAATATTTCGCAGGTCTTGGATATGACGGTCAACGATGCGGTAGAATTTTTC
CAACACATTCCGAAAATTCAACGCAAACTCCAGACCATCAAGGATGTAGGTCTAGGCTATGTGACCTTGGGACAGCCAGC
TACCACCCTTTCTGGGGGAGAAGCCCAACGTATGAAGTTAGCTAGCGAACTCCACAAACGCTCGACAGGAAAATCTTTCT
ACATTCTGGATGAGCCGACGACAGGGCTTCATACAGAGGACATTGCTCGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGAC
GCCGGCAATACAGTCCTCGTCATCGAGCACAATCTGGATGTTATCAAGACGGCAGACCATATCATTGACTTGGGACCTGA
GGGCGGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAACGAAGCCAGCTATACAGGAC
ACTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (132-238)

• ABC transporter (ABC_tran) (624-860)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	99.682	100	0.997
uvrA	Streptococcus pneumoniae TIGR4	99.682	100	0.997
uvrA	Streptococcus pneumoniae D39	99.682	100	0.997