Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R4705_RS03980 Genome accession   NZ_CP137115
Coordinates   749565..750389 (-) Length   274 a.a.
NCBI ID   WP_001036787.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20614-6     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 744565..755389
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS03975 - 747943..749274 (-) 1332 WP_000390039.1 hemolysin family protein -
  R4705_RS03980 endA 749565..750389 (-) 825 WP_001036787.1 DNA-entry nuclease EndA Machinery gene
  R4705_RS03985 - 750428..750616 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  R4705_RS03990 murA 750609..751892 (-) 1284 WP_279513424.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R4705_RS03995 - 751916..752146 (-) 231 WP_000250384.1 DUF1146 family protein -
  R4705_RS04000 sepM 752204..753241 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  R4705_RS04005 coaD 753225..753713 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  R4705_RS04010 rsmD 753703..754242 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R4705_RS04015 asnA 754307..755299 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29917.60 Da        Isoelectric Point: 10.1197

>NTDB_id=896249 R4705_RS03980 WP_001036787.1 749565..750389(-) (endA) [Streptococcus pneumoniae strain 20614-6]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQGPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=896249 R4705_RS03980 WP_001036787.1 749565..750389(-) (endA) [Streptococcus pneumoniae strain 20614-6]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGGGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989