Detailed information NTG0896097

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R4707_RS04390
• Genome accession: NZ_CP137113
• Coordinates: 818988..819998 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain ZGX
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 813988..824998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4707_RS04365	-	815249..815542 (-)	294	WP_044814358.1	hypothetical protein	-
R4707_RS04370	-	815699..816151 (+)	453	WP_000079148.1	universal stress protein	-
R4707_RS04375	-	816186..817574 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
R4707_RS04380	-	817640..818602 (+)	963	WP_050103781.1	asparaginase	-
R4707_RS04385	-	818631..818924 (-)	294	WP_050103772.1	hypothetical protein	-
R4707_RS04390	ccpA	818988..819998 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R4707_RS04395	-	820423..821022 (-)	600	WP_081542926.1	response regulator transcription factor	-
R4707_RS04400	-	821024..822121 (-)	1098	WP_050103770.1	sensor histidine kinase	-
R4707_RS04405	-	822121..822858 (-)	738	WP_000832839.1	ABC transporter permease	-
R4707_RS04410	-	822860..823744 (-)	885	WP_000219353.1	ABC transporter ATP-binding protein	-
R4707_RS04415	-	823731..823925 (-)	195	WP_000715301.1	hypothetical protein	-
R4707_RS04420	-	823922..824128 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=896097 R4707_RS04390 WP_000990607.1 818988..819998(-) (ccpA) [Streptococcus pneumoniae strain ZGX]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=896097 R4707_RS04390 WP_000990607.1 818988..819998(-) (ccpA) [Streptococcus pneumoniae strain ZGX]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568