Detailed information NTG0895964

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: R4706_RS06800
• Genome accession: NZ_CP137111
• Coordinates: 1339222..1340259 (+)
• Length: 345 a.a.
• NCBI ID: WP_000727277.1
• Uniprot ID: A0A0B7LHQ0
• Organism: Streptococcus pneumoniae strain 17023
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1334222..1345259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4706_RS06765	yidC	1334257..1335183 (-)	927	WP_000835955.1	membrane protein insertase YidC	-
R4706_RS06770	-	1335261..1335539 (-)	279	WP_044727708.1	acylphosphatase	-
R4706_RS06775	-	1335573..1336313 (+)	741	WP_044727707.1	RNA methyltransferase	-
R4706_RS06780	-	1336369..1337052 (+)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
R4706_RS06785	asnA	1337164..1338156 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
R4706_RS06790	rsmD	1338221..1338760 (+)	540	WP_000706964.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
R4706_RS06795	coaD	1338750..1339238 (+)	489	WP_001280723.1	pantetheine-phosphate adenylyltransferase	-
R4706_RS06800	sepM	1339222..1340259 (+)	1038	WP_000727277.1	SepM family pheromone-processing serine protease	Regulator
R4706_RS06805	-	1340317..1340547 (+)	231	WP_000250393.1	DUF1146 family protein	-
R4706_RS06810	murA	1340571..1341854 (+)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
R4706_RS06815	-	1341847..1342035 (+)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
R4706_RS06820	endA	1342074..1342898 (+)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
R4706_RS06825	-	1343189..1344520 (+)	1332	WP_000390040.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37537.57 Da
• Isoelectric Point: 5.0724

>NTDB_id=895964 R4706_RS06800 WP_000727277.1 1339222..1340259(+) (sepM) [Streptococcus pneumoniae strain 17023]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=895964 R4706_RS06800 WP_000727277.1 1339222..1340259(+) (sepM) [Streptococcus pneumoniae strain 17023]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGGAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

3D structure

• AlphaFold DB: A0A0B7LHQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591