Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R4712_RS06760 Genome accession   NZ_CP137110
Coordinates   1321798..1322622 (+) Length   274 a.a.
NCBI ID   WP_317818415.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2041     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1316798..1327622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS06725 asnA 1316888..1317880 (+) 993 WP_044791888.1 aspartate--ammonia ligase -
  R4712_RS06730 rsmD 1317945..1318484 (+) 540 WP_044788620.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R4712_RS06735 coaD 1318474..1318962 (+) 489 WP_001280736.1 pantetheine-phosphate adenylyltransferase -
  R4712_RS06740 sepM 1318946..1319983 (+) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  R4712_RS06745 - 1320041..1320271 (+) 231 WP_001809307.1 DUF1146 family protein -
  R4712_RS06750 murA 1320295..1321578 (+) 1284 WP_000358027.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R4712_RS06755 - 1321571..1321759 (+) 189 WP_001812859.1 DNA-directed RNA polymerase subunit beta -
  R4712_RS06760 endA 1321798..1322622 (+) 825 WP_317818415.1 DNA-entry nuclease EndA Machinery gene
  R4712_RS06765 - 1322913..1324244 (+) 1332 WP_000390042.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 30007.72 Da        Isoelectric Point: 10.1089

>NTDB_id=895884 R4712_RS06760 WP_317818415.1 1321798..1322622(+) (endA) [Streptococcus pneumoniae strain 16H2041]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETENGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=895884 R4712_RS06760 WP_317818415.1 1321798..1322622(+) (endA) [Streptococcus pneumoniae strain 16H2041]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGAGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989