Detailed information NTG0895744

Bioinformatically predicted

Overview

• Name: hexB
• Type: Machinery gene
• Locus tag: ABC964_RS06490
• Genome accession: NZ_CP155060
• Coordinates: 1321694..1322860 (+)
• Length: 388 a.a.
• NCBI ID: WP_001806223.1
• Uniprot ID: B1VKA9
• Organism: Staphylococcus aureus strain CC5-MSSA
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1316694..1327860

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC964_RS06475 (ABC964_06475)	-	1317877..1318242 (+)	366	WP_000282386.1	RicAFT regulatory complex protein RicA family protein	-
ABC964_RS06480 (ABC964_06480)	thiW	1318269..1318760 (+)	492	WP_000842277.1	energy coupling factor transporter S component ThiW	-
ABC964_RS06485 (ABC964_06485)	hexA	1319063..1321681 (+)	2619	WP_000073352.1	DNA mismatch repair protein MutS	Machinery gene
ABC964_RS06490 (ABC964_06490)	hexB	1321694..1322860 (+)	1167	WP_001806223.1	DNA mismatch repair endonuclease MutL	Machinery gene
ABC964_RS06495 (ABC964_06495)	-	1322833..1323702 (+)	870	WP_001806221.1	DNA mismatch repair protein	-
ABC964_RS06500 (ABC964_06500)	-	1323708..1324250 (+)	543	WP_001077635.1	glycerol-3-phosphate responsive antiterminator	-
ABC964_RS06505 (ABC964_06505)	-	1324725..1325543 (+)	819	WP_001103743.1	MIP/aquaporin family protein	-
ABC964_RS06510 (ABC964_06510)	glpK	1325672..1327168 (+)	1497	WP_000417372.1	glycerol kinase GlpK	-

Sequence

Protein

• Length: 388 a.a.
• Molecular weight: 43902.64 Da
• Isoelectric Point: 9.7302

>NTDB_id=895744 ABC964_RS06490 WP_001806223.1 1321694..1322860(+) (hexB) [Staphylococcus aureus strain CC5-MSSA]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKIKYYIHSNNKKSNLNKDKTQRITKRRRFHLKKVTVSHLWQKIKTMR

Nucleotide

• Length: 1167 bp

>NTDB_id=895744 ABC964_RS06490 WP_001806223.1 1321694..1322860(+) (hexB) [Staphylococcus aureus strain CC5-MSSA]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAATAGAATGGCTATGAGCCATCCGGACATTCGAATAGC
ACTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGCTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATATCAATTGATAGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCAAAAAAAATAAAGTATTATAT
TCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAGA
AAGTAACAGTAAGTCATTTATGGCAGAAAATCAAAACGATGAGATAG

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3) (25-119)

• DNA mismatch repair protein, C-terminal domain (DNA_mis_repair) (209-325)

3D structure

• AlphaFold DB: B1VKA9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexB	Streptococcus pneumoniae R6	53.153	85.825	0.456