Detailed information NTG0895605

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: R4711_RS01010
• Genome accession: NZ_CP137107
• Coordinates: 204873..207113 (-)
• Length: 746 a.a.
• NCBI ID: WP_000942425.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 15H4024
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 199873..212113

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4711_RS00975	-	200782..201162 (-)	381	WP_000157154.1	VOC family protein	-
R4711_RS00980	rplT	201220..201579 (-)	360	WP_000124836.1	50S ribosomal protein L20	-
R4711_RS00985	rpmI	201631..201831 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
R4711_RS00990	infC	201864..202394 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
R4711_RS00995	-	202701..203882 (-)	1182	WP_054395574.1	hypothetical protein	-
R4711_RS01000	-	203886..204473 (-)	588	WP_000939884.1	ATP-binding cassette domain-containing protein	-
R4711_RS01005	-	204506..204694 (-)	189	WP_044812623.1	hypothetical protein	-
R4711_RS01010	comEC/celB	204873..207113 (-)	2241	WP_000942425.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
R4711_RS01015	comEA/celA/cilE	207097..207747 (-)	651	WP_000387332.1	helix-hairpin-helix domain-containing protein	Machinery gene
R4711_RS01020	-	207815..208384 (-)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
R4711_RS01025	ald	208561..209672 (+)	1112	Protein_204	alanine dehydrogenase	-
R4711_RS01030	-	209973..210299 (-)	327	Protein_205	TfoX/Sxy family protein	-
R4711_RS01035	-	210302..210802 (-)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
R4711_RS01040	-	210995..211963 (-)	969	WP_000658183.1	PhoH family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84595.12 Da
• Isoelectric Point: 9.5123

>NTDB_id=895605 R4711_RS01010 WP_000942425.1 204873..207113(-) (comEC/celB) [Streptococcus pneumoniae strain 15H4024]
MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCLFFQFPWKSAGKVLVICGVFGFWFLFQNWQQSQASQN
LADSVERVRILPDTVKVNGDSLSFRGKADGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVFLLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLISLPLVYDLRKNIKGLTVLSLLITGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=895605 R4711_RS01010 WP_000942425.1 204873..207113(-) (comEC/celB) [Streptococcus pneumoniae strain 15H4024]
ATGTTACAGTGGATTAAGAACATCCCCATTCCCCTAATTTACCTGAGTTTTTTGTTACTTTGGTTTTATTACGCTATTTT
CTCAGCATCCTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCATGGAAATCAGCAG
GCAAAGTTTTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGCCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTCTGCCTGACACTGTTAAGGTCAATGGTGATAGTCTGTCCTTTCGCGGCAA
GGCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACAGTGTTTCTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
CTCACAGGTGGCAAGTAGGCCTCTAGTCTTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGCCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGGGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-457)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	97.453	100	0.975
comEC/celB	Streptococcus pneumoniae D39	97.453	100	0.975
comEC/celB	Streptococcus pneumoniae R6	97.453	100	0.975
comEC/celB	Streptococcus pneumoniae TIGR4	97.319	100	0.973
comEC/celB	Streptococcus mitis SK321	91.689	100	0.917
comEC/celB	Streptococcus mitis NCTC 12261	91.275	99.866	0.912
comEC	Lactococcus lactis subsp. cremoris KW2	43.952	99.732	0.438