Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   R4699_RS00585 Genome accession   NZ_CP137105
Coordinates   95085..96152 (+) Length   355 a.a.
NCBI ID   WP_000159553.1    Uniprot ID   A0A0T8CF10
Organism   Streptococcus pneumoniae strain 16H2092     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 90085..101152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4699_RS00570 amiA3 90608..92587 (+) 1980 WP_000742234.1 peptide ABC transporter substrate-binding protein Regulator
  R4699_RS00575 amiC 92654..94150 (+) 1497 WP_044793554.1 ABC transporter permease Regulator
  R4699_RS00580 amiD 94150..95076 (+) 927 WP_000103700.1 oligopeptide ABC transporter permease OppC Regulator
  R4699_RS00585 amiE 95085..96152 (+) 1068 WP_000159553.1 ABC transporter ATP-binding protein Regulator
  R4699_RS00590 amiF 96163..97089 (+) 927 WP_001291293.1 ATP-binding cassette domain-containing protein Regulator
  R4699_RS00595 - 97164..98490 (-) 1327 Protein_96 ISL3 family transposase -
  R4699_RS00600 treR 98646..99356 (-) 711 WP_000760673.1 trehalose operon repressor Regulator

Sequence

Protein


Download         Length: 355 a.a.        Molecular weight: 39437.04 Da        Isoelectric Point: 4.8002

>NTDB_id=895460 R4699_RS00585 WP_000159553.1 95085..96152(+) (amiE) [Streptococcus pneumoniae strain 16H2092]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide


Download         Length: 1068 bp        

>NTDB_id=895460 R4699_RS00585 WP_000159553.1 95085..96152(+) (amiE) [Streptococcus pneumoniae strain 16H2092]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-301)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8CF10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

88.451

100

0.885
  amiE Streptococcus thermophilus LMG 18311

86.761

100

0.868
  amiE Streptococcus thermophilus LMD-9

86.761

100

0.868
  oppD Streptococcus mutans UA159

54.545

99.155

0.541