Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   R4708_RS00635 Genome accession   NZ_CP137104
Coordinates   140207..141016 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain LM     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 135207..146016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4708_RS00610 - 135841..136827 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  R4708_RS00615 - 137136..138482 (+) 1347 WP_001821303.1 IS1380-like element ISSpn5 family transposase -
  R4708_RS00620 - 138798..139571 (-) 774 WP_000731129.1 potassium channel family protein -
  R4708_RS00625 - 139618..139872 (-) 255 WP_001812387.1 type II toxin-antitoxin system RelE/ParE family toxin -
  R4708_RS00630 relB 139874..140116 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  R4708_RS00635 vicX 140207..141016 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  R4708_RS00640 micB 141018..142367 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R4708_RS00645 micA 142360..143064 (-) 705 WP_000722076.1 response regulator YycF Regulator
  R4708_RS00650 mutY 143119..144294 (-) 1176 WP_000886147.1 A/G-specific adenine glycosylase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=895374 R4708_RS00635 WP_001289493.1 140207..141016(-) (vicX) [Streptococcus pneumoniae strain LM]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=895374 R4708_RS00635 WP_001289493.1 140207..141016(-) (vicX) [Streptococcus pneumoniae strain LM]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773