Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   R4713_RS00580 Genome accession   NZ_CP137103
Coordinates   109752..111563 (-) Length   603 a.a.
NCBI ID   WP_050237438.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21334     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 104752..116563
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4713_RS00545 - 104867..105709 (+) 843 WP_000954117.1 DUF368 domain-containing protein -
  R4713_RS00550 - 105709..106190 (+) 482 Protein_107 aminoacyl-tRNA deacylase -
  R4713_RS00555 - 106190..106810 (+) 621 WP_000780813.1 histidine phosphatase family protein -
  R4713_RS00560 - 107063..107158 (-) 96 Protein_109 IS630 family transposase -
  R4713_RS00565 - 107571..107912 (+) 342 Protein_110 transposase -
  R4713_RS00570 prsA 108029..108970 (-) 942 WP_000727935.1 peptidylprolyl isomerase PrsA -
  R4713_RS00575 - 109037..109750 (-) 714 WP_000230400.1 O-methyltransferase -
  R4713_RS00580 pepF 109752..111563 (-) 1812 WP_050237438.1 oligoendopeptidase F Regulator
  R4713_RS00585 coiA 111582..112535 (-) 954 WP_000495909.1 competence protein CoiA Machinery gene
  R4713_RS00590 tehB 112608..113468 (-) 861 WP_000413757.1 SAM-dependent methyltransferase TehB -
  R4713_RS00595 smpB 113484..113951 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -
  R4713_RS00600 rnr 113914..116268 (-) 2355 WP_000654886.1 ribonuclease R -

Sequence

Protein


Download         Length: 603 a.a.        Molecular weight: 70251.18 Da        Isoelectric Point: 4.5274

>NTDB_id=895299 R4713_RS00580 WP_050237438.1 109752..111563(-) (pepF) [Streptococcus pneumoniae strain 21334]
MVLQRNEINEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQMEKLYVYAHM
KNDQDTREAKYQEYYAKAMTLYSQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELL
AGAGEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNV
KVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQE
ALKKAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYT
RETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLT
SDFLNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSD
YPLNVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1812 bp        

>NTDB_id=895299 R4713_RS00580 WP_050237438.1 109752..111563(-) (pepF) [Streptococcus pneumoniae strain 21334]
ATGGTATTACAAAGAAATGAAATAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCA
GGCTTGGGAAGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTG
CGGATAACCTACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATGGAGAAGCTTTACGTTTATGCTCATATG
AAGAATGACCAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCA
AGCCTTTTCATTCTATGATCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGC
TGCAGGTTTATCAACACTATTTTGACAAGCTCTTGCAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTG
GCTGGAGCTGGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGT
CCTAGACGATGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTC
GCCGTGGTGCCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTT
AAGGTGCAAAATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGA
AAGTGTTTATGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAA
TCTTGGGGATTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAATTTTACCTACCAAGAA
GCCTTGAAAAAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTCAAACGTGCCTTCAGCGAGCG
TTGGATTGATGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTACGATACCAATGCCTTTATGC
TTCTCAACTGGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACT
CGTGAAACTCAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTT
GACGGAGAAATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTG
GAACAGTTTTCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACA
AGCGATTTCCTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCA
ATACGAGTGGGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGGCCGCCTCAG
CCTTGGCTGAAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGAC
TATCCACTTAATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGA
ACGCCGTTTAAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(205-584)

Oligopeptidase F (Peptidase_M3_N)

(115-184)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.742

97.678

0.662