Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R4709_RS06960 Genome accession   NZ_CP137102
Coordinates   1343844..1344668 (+) Length   274 a.a.
NCBI ID   WP_001036783.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H3071-2     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1338844..1349668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4709_RS06925 asnA 1338934..1339926 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  R4709_RS06930 rsmD 1339991..1340530 (+) 540 WP_000706960.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R4709_RS06935 coaD 1340520..1341008 (+) 489 WP_001280723.1 pantetheine-phosphate adenylyltransferase -
  R4709_RS06940 sepM 1340992..1342029 (+) 1038 WP_000727268.1 SepM family pheromone-processing serine protease Regulator
  R4709_RS06945 - 1342087..1342317 (+) 231 WP_000250393.1 DUF1146 family protein -
  R4709_RS06950 murA 1342341..1343624 (+) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R4709_RS06955 - 1343617..1343805 (+) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  R4709_RS06960 endA 1343844..1344668 (+) 825 WP_001036783.1 DNA-entry nuclease EndA Machinery gene
  R4709_RS06965 - 1344959..1346290 (+) 1332 WP_000390043.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.66 Da        Isoelectric Point: 10.1700

>NTDB_id=895271 R4709_RS06960 WP_001036783.1 1343844..1344668(+) (endA) [Streptococcus pneumoniae strain 16H3071-2]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=895271 R4709_RS06960 WP_001036783.1 1343844..1344668(+) (endA) [Streptococcus pneumoniae strain 16H3071-2]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.27

100

0.993
  endA Streptococcus pneumoniae D39

99.27

100

0.993
  endA Streptococcus pneumoniae R6

99.27

100

0.993
  endA Streptococcus pneumoniae TIGR4

99.27

100

0.993