Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R4710_RS05525 Genome accession   NZ_CP137101
Coordinates   1041173..1041835 (-) Length   220 a.a.
NCBI ID   WP_000649974.1    Uniprot ID   A0A0F7YBW3
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1036173..1046835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS05500 - 1036323..1036589 (-) 267 WP_001278167.1 Veg family protein -
  R4710_RS05505 dnaB 1036591..1037943 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R4710_RS05510 rplI 1037987..1038439 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R4710_RS05515 - 1038436..1040409 (-) 1974 WP_000715109.1 DHH family phosphoesterase -
  R4710_RS05520 hpf 1040545..1041093 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R4710_RS05525 comFC/cflB 1041173..1041835 (-) 663 WP_000649974.1 ComF family protein Machinery gene
  R4710_RS05530 comFA/cflA 1041832..1043130 (-) 1299 WP_000867605.1 DEAD/DEAH box helicase Machinery gene
  R4710_RS05535 - 1043186..1043821 (+) 636 WP_000395739.1 YigZ family protein -
  R4710_RS05540 cysK 1044106..1045026 (+) 921 WP_000029866.1 cysteine synthase A -
  R4710_RS05545 - 1045101..1045593 (-) 493 Protein_1053 transposase -
  R4710_RS05550 - 1045566..1045874 (+) 309 Protein_1054 transposase -
  R4710_RS05555 tnpB 1046010..1046351 (-) 342 WP_050208954.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25169.03 Da        Isoelectric Point: 7.7116

>NTDB_id=895188 R4710_RS05525 WP_000649974.1 1041173..1041835(-) (comFC/cflB) [Streptococcus pneumoniae strain 16P2012-2]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=895188 R4710_RS05525 WP_000649974.1 1041173..1041835(-) (comFC/cflB) [Streptococcus pneumoniae strain 16P2012-2]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAATTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

100

100

1
  comFC/cflB Streptococcus pneumoniae D39

100

100

1
  comFC/cflB Streptococcus pneumoniae R6

100

100

1
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909