Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   R4710_RS03625 Genome accession   NZ_CP137101
Coordinates   698875..699942 (-) Length   355 a.a.
NCBI ID   WP_000159554.1    Uniprot ID   A0A062WMA1
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 693875..704942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS03610 treR 695722..696432 (+) 711 WP_000760673.1 trehalose operon repressor Regulator
  R4710_RS03615 - 696587..697863 (+) 1277 WP_404969405.1 ISL3 family transposase -
  R4710_RS03620 amiF 697938..698864 (-) 927 WP_001291294.1 ATP-binding cassette domain-containing protein Regulator
  R4710_RS03625 amiE 698875..699942 (-) 1068 WP_000159554.1 ABC transporter ATP-binding protein Regulator
  R4710_RS03630 amiD 699951..700877 (-) 927 WP_044812043.1 oligopeptide ABC transporter permease OppC Regulator
  R4710_RS03635 amiC 700877..702373 (-) 1497 WP_000759905.1 ABC transporter permease Regulator
  R4710_RS03640 amiA3 702440..704419 (-) 1980 WP_000742233.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 355 a.a.        Molecular weight: 39490.09 Da        Isoelectric Point: 4.8727

>NTDB_id=895160 R4710_RS03625 WP_000159554.1 698875..699942(-) (amiE) [Streptococcus pneumoniae strain 16P2012-2]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide


Download         Length: 1068 bp        

>NTDB_id=895160 R4710_RS03625 WP_000159554.1 698875..699942(-) (amiE) [Streptococcus pneumoniae strain 16P2012-2]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-301)

ABC transporter (ABC_tran)

(29-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A062WMA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

88.169

100

0.882
  amiE Streptococcus thermophilus LMG 18311

86.479

100

0.865
  amiE Streptococcus thermophilus LMD-9

86.479

100

0.865
  oppD Streptococcus mutans UA159

54.545

99.155

0.541