Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   AAVB74_RS14740 Genome accession   NZ_CP154920
Coordinates   2770432..2772315 (-) Length   627 a.a.
NCBI ID   WP_088325893.1    Uniprot ID   -
Organism   Bacillus subtilis strain FUA2232     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2765432..2777315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAVB74_RS14710 (AAVB74_14710) fabD 2766023..2766889 (-) 867 WP_038428987.1 ACP S-malonyltransferase -
  AAVB74_RS14715 (AAVB74_14715) - 2766886..2767152 (-) 267 WP_120028100.1 hypothetical protein -
  AAVB74_RS14720 (AAVB74_14720) pksB 2767262..2767939 (-) 678 WP_003231824.1 MBL fold metallo-hydrolase -
  AAVB74_RS14725 (AAVB74_14725) pksA 2768129..2768746 (-) 618 WP_116315489.1 TetR/AcrR family transcriptional regulator -
  AAVB74_RS14730 (AAVB74_14730) - 2768866..2769423 (+) 558 WP_086343851.1 hypothetical protein -
  AAVB74_RS14735 (AAVB74_14735) ymzD 2769579..2770034 (+) 456 WP_015252068.1 regulatory YrvL family protein -
  AAVB74_RS14740 (AAVB74_14740) hexB 2770432..2772315 (-) 1884 WP_088325893.1 DNA mismatch repair endonuclease MutL Machinery gene
  AAVB74_RS14745 (AAVB74_14745) hexA 2772331..2774907 (-) 2577 WP_088325891.1 DNA mismatch repair protein MutS Machinery gene
  AAVB74_RS14750 (AAVB74_14750) cotE 2775040..2775585 (-) 546 WP_003231833.1 outer spore coat protein CotE -
  AAVB74_RS14755 (AAVB74_14755) ymcA 2775848..2776279 (-) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70582.51 Da        Isoelectric Point: 5.6795

>NTDB_id=895134 AAVB74_RS14740 WP_088325893.1 2770432..2772315(-) (hexB) [Bacillus subtilis strain FUA2232]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPAIKNEQQFITFDEKPPERKVPEKAHAPSYSPMKLSSVVKEPIDAEEELPPLQFDAPPI
VDQEQTLEVSDVSEELPETFEQECHEEQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=895134 AAVB74_RS14740 WP_088325893.1 2770432..2772315(-) (hexB) [Bacillus subtilis strain FUA2232]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGAACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTTGCGCATCCAGAGGTATCGATTCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAATGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCTTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTGAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCAATTACCTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATACGTGACGGA
ATTAAAGATGTGTTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGCCATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAGAAAAGTACCGGAAAAAGCGCATGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGATTGATGCGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGAAGAACTGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGTCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGTGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGCTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTCATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTTCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATACACC
ATTCCACTTATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

MutL C terminal dimerisation domain (MutL_C)

(442-583)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.201

100

0.466