Detailed information NTG0895003

Bioinformatically predicted

Overview

• Name: amiC
• Type: Regulator
• Locus tag: R4714_RS03370
• Genome accession: NZ_CP137099
• Coordinates: 646844..648340 (-)
• Length: 498 a.a.
• NCBI ID: WP_000759901.1
• Uniprot ID: P0A4M7
• Organism: Streptococcus pneumoniae strain 20824-4
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 641844..653340

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4714_RS03350	-	642504..643780 (+)	1277	WP_398579129.1	ISL3 family transposase	-
R4714_RS03355	amiF	643905..644831 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
R4714_RS03360	amiE	644842..645909 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
R4714_RS03365	amiD	645918..646844 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
R4714_RS03370	amiC	646844..648340 (-)	1497	WP_000759901.1	ABC transporter permease	Regulator
R4714_RS03375	amiA3	648407..650386 (-)	1980	WP_219576943.1	peptide ABC transporter substrate-binding protein	Regulator
R4714_RS03380	-	651074..652267 (-)	1194	WP_000835622.1	O-antigen ligase	-

Sequence

Protein

• Length: 498 a.a.
• Molecular weight: 55623.17 Da
• Isoelectric Point: 9.4436

>NTDB_id=895003 R4714_RS03370 WP_000759901.1 646844..648340(-) (amiC) [Streptococcus pneumoniae strain 20824-4]
MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYNKIATTADKRDNYENTVFERMGYIEYYDTKELQEKAS
SMDSSVTVEANATNKAIYEKYINQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVITQGQGQTKTAQVQFPTGKKTSSV
NIYSRTYKSPSQADSREVASYGKDDPYTATESNYQYPSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGA
LTFLLALPTIALVYIVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFVRFARAKGL
SEKEISNKHIFKNAMVPLVSGIPAAIIGVIGGATLTETVFAFPGMGKMLIDSVKASNNSMVVGLVFIFTCISIFSRLLGD
IWMTIIDPRIKLTEKGGK

Nucleotide

• Length: 1497 bp

>NTDB_id=895003 R4714_RS03370 WP_000759901.1 646844..648340(-) (amiC) [Streptococcus pneumoniae strain 20824-4]
ATGAAAAAATATATTTTTATGCGTGTTTTGCGGTCATTGGTTTCGATTTTCTTAGTAACGACTTTGACCTACACGATTAT
CTATACCTTGGTTCCTCGAAAATTGATTTTCAAGCAGGATCCTAACTATAATAAAATTGCGACAACGGCTGATAAACGTG
ATAACTATGAAAATACTGTGTTTGAGCGTATGGGCTACATTGAGTATTACGATACTAAAGAGTTGCAAGAAAAGGCAAGT
AGCATGGATTCTTCTGTAACAGTAGAAGCAAATGCGACCAATAAAGCTATTTATGAAAAGTACATCAATCAATTAGGTCA
TGGTTGGACTTTGGGAGAATTTACTGAAAGTGGTCAATTCTATGCTACTCGTGAAATTCCAATTTTTGAACGTGTTTTTC
ACTTCTATGCTAACTTGATTGACATTGACCATACAAATAAAATCCAAGACCCTGAAAATCCAGACTTGAAACGCTACCTT
CGTTTTGAAAATGATCCAGCTATCGGATGGTCATTGGTCGGTTCAGGAACTAAACATAAATATCTCTTGTACTTTAACAG
TCAGTTCCCATTTGTTCATCAAAACTTTGTGAACTTGAATTTAGGTGACTCTTACCCAACCTATGCTAATACACCAGTTC
TTCAGGTTATTACTCAAGGTCAAGGACAAACCAAAACTGCCCAAGTTCAGTTCCCAACAGGTAAGAAAACGTCTTCTGTA
AATATTTACTCAAGAACCTACAAGTCACCTAGTCAGGCTGACTCTCGTGAAGTAGCTAGCTATGGGAAAGATGATCCTTA
TACAGCGACTGAAAGTAATTACCAATATCCATCTATGATTGTCAGCTCTGCTATTACTGGTTTGATTGGTTTGGTTCTTG
CCTATGCTCTTGCCGTGCCACTTGGTTCAGCCATGGCTCGTTTCAAGAACACTTGGATTGATAGCCTCTCAACAGGGGCT
TTGACCTTCTTGCTTGCTCTTCCAACGATTGCCTTGGTTTACATCGTTCGATTGATTGGATCATCTATTGCCCTTCCAGA
TTCATTCCCTATCTTGGGAGCTGGAGATTGGCGTTCTTACGTTTTACCAGCAGTCATCCTTGGTTTGTTGGGTGCTCCTG
GTACAGCCATTTGGATTCGTCGTTACATGATTGACTTGCAATCTCAAGACTTTGTTCGTTTCGCTCGTGCAAAAGGTTTG
TCTGAAAAAGAAATTTCAAACAAACACATCTTTAAAAATGCCATGGTTCCGCTGGTTTCAGGAATTCCTGCTGCCATTAT
TGGGGTTATCGGTGGTGCAACCCTTACTGAAACAGTCTTCGCCTTCCCAGGTATGGGTAAAATGTTGATTGACTCTGTAA
AAGCATCTAATAACTCTATGGTCGTTGGTCTTGTCTTCATCTTTACATGTATTTCTATCTTCTCACGTCTTTTGGGAGAT
ATTTGGATGACTATTATTGACCCACGTATTAAATTGACTGAGAAAGGAGGCAAATAA

Domains

Predicted by InterproScan.

• Binding-protein-dependent transport system inner membrane component (BPD_transp_1) (298-491)

3D structure

• AlphaFold DB: P0A4M7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiC	Streptococcus salivarius strain HSISS4	77.309	100	0.773
amiC	Streptococcus thermophilus LMG 18311	77.108	100	0.771
amiC	Streptococcus thermophilus LMD-9	76.707	100	0.767