Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   R4535_RS11605 Genome accession   NZ_CP137091
Coordinates   2568707..2569339 (+) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae strain DL4211     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2563707..2574339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4535_RS11580 (R4535_11555) - 2563772..2565688 (+) 1917 WP_032472758.1 ABC transporter ATP-binding protein -
  R4535_RS11585 (R4535_11560) - 2565689..2566174 (+) 486 WP_001278735.1 TIGR02444 family protein -
  R4535_RS11590 (R4535_11565) - 2566171..2567160 (+) 990 WP_000206394.1 hydrolase -
  R4535_RS11595 (R4535_11570) - 2567289..2567498 (+) 210 WP_076024944.1 YheU family protein -
  R4535_RS11600 (R4535_11575) - 2567595..2568464 (+) 870 WP_001274667.1 phosphoribulokinase -
  R4535_RS11605 (R4535_11580) crp 2568707..2569339 (+) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  R4535_RS11610 (R4535_11585) - 2569418..2570209 (-) 792 WP_032477730.1 DUF1338 domain-containing protein -
  R4535_RS11615 (R4535_11590) astD 2570352..2571809 (-) 1458 WP_076024943.1 succinylglutamate-semialdehyde dehydrogenase -
  R4535_RS11620 (R4535_11595) astA 2571819..2572838 (-) 1020 WP_076024942.1 arginine N-succinyltransferase -
  R4535_RS11625 (R4535_11600) - 2572978..2574189 (-) 1212 WP_000215475.1 aspartate aminotransferase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=894968 R4535_RS11605 WP_000242749.1 2568707..2569339(+) (crp) [Vibrio cholerae strain DL4211]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=894968 R4535_RS11605 WP_000242749.1 2568707..2569339(+) (crp) [Vibrio cholerae strain DL4211]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAGTTAAT
TCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGATGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467