Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   AAVD18_RS05250 Genome accession   NZ_CP154893
Coordinates   947640..949517 (+) Length   625 a.a.
NCBI ID   WP_013352326.1    Uniprot ID   A0A9P1JH09
Organism   Bacillus amyloliquefaciens strain Fad 11/2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 942640..954517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAVD18_RS05235 (AAVD18_05235) ymcA 943693..944124 (+) 432 WP_013352323.1 RicAFT regulatory complex protein RicA family protein Regulator
  AAVD18_RS05240 (AAVD18_05240) cotE 944378..944923 (+) 546 WP_013352324.1 outer spore coat protein CotE -
  AAVD18_RS05245 (AAVD18_05245) hexA 945039..947624 (+) 2586 WP_014470386.1 DNA mismatch repair protein MutS Machinery gene
  AAVD18_RS05250 (AAVD18_05250) hexB 947640..949517 (+) 1878 WP_013352326.1 DNA mismatch repair endonuclease MutL Machinery gene
  AAVD18_RS05255 (AAVD18_05255) - 949983..950659 (+) 677 Protein_1029 MBL fold metallo-hydrolase -
  AAVD18_RS05260 (AAVD18_05260) fabD 950964..951833 (+) 870 WP_013352328.1 ACP S-malonyltransferase -
  AAVD18_RS05265 (AAVD18_05265) - 951968..952942 (+) 975 WP_013352329.1 acyltransferase domain-containing protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 70353.50 Da        Isoelectric Point: 5.9217

>NTDB_id=894372 AAVD18_RS05250 WP_013352326.1 947640..949517(+) (hexB) [Bacillus amyloliquefaciens strain Fad 11/2]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDANSTVIEIDIEEAGLSSIRVLDNGEGMETEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEIKTSIGEGAGTHLILQGGNMISEQRTSSRKGTEIIVTNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHQGKNLLQTNGNGDVRHVLAAIYGTAVAKKMIPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVINGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHELIRDG
IKEVFQKQRLIPSAQLPKKSAPAPIKNEQQFMTFGESEPERKLPEKTPEPSYSPMKLSSVVKEPAPVTEEEFHPNEADHE
VPSETSMPEMAAPVSDIPAPEEEAVSEEIQEERVPVMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVGQV
EPEVQDMIVPLTFHYAANEALIIEQHQHELESVGVFLEAFGTNSYIVRCHPAWFPKGEEAELIEEIIQQVLDAKQIDIKK
LREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRRTADPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=894372 AAVD18_RS05250 WP_013352326.1 947640..949517(+) (hexB) [Bacillus amyloliquefaciens strain Fad 11/2]
TTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCCGGTGAGGTGGTGGAACGGCCCGCCTCTGT
CGTTAAAGAATTGGTGGAAAACGCAATCGACGCAAACAGCACAGTCATTGAAATCGATATAGAGGAAGCGGGGCTTTCGT
CGATTCGGGTGCTCGACAACGGCGAAGGTATGGAAACCGAGGATTGCAAGCGGGCTTTCCGCCGCCATGCGACCAGTAAA
ATCAAAGATGAAAATGACCTGTTCCGGGTGAGAACACTCGGTTTCCGCGGAGAAGCTTTGCCAAGTATCGCGTCTGTTTC
TCATCTGGAAATCAAAACGAGCATCGGCGAGGGAGCGGGAACTCATCTCATTCTTCAGGGCGGGAATATGATTTCTGAAC
AGAGAACTTCCAGCAGAAAAGGGACGGAGATCATCGTCACTAACCTGTTTTTCAATACACCCGCCAGATTAAAATATATG
AAAACCGTGCATACGGAGCTCGGCAATATTACGGATGTCGTCAACCGGATCGCTCTTGCGCATCCGGAAGTATCGATCCG
CCTCCGCCATCAGGGGAAAAACCTGCTGCAGACAAACGGAAACGGGGACGTGCGCCATGTGCTGGCCGCAATTTACGGGA
CGGCGGTTGCGAAAAAAATGATACCGCTCCATGTCAGCTCACTTGATTTTGAAGTCAAGGGCTACATTGCGCTGCCGGAA
ATCACGCGTGCATCCAGAAACTACATGTCATCTGTCATTAACGGAAGATACATTAAGAATTTCCCGCTTGTAAAAGCGGT
GCATGAGGGCTATCACACGCTTCTGCCGATCGGCCGCCATCCGATTACGTTTATCGAAATTACGATGGATCCGATTTTAG
TCGATGTCAATGTCCATCCGTCGAAGCTTGAAGTCCGCCTCAGCAAAGAGACGGAACTGCATGAGCTGATCCGTGACGGC
ATAAAGGAAGTTTTTCAAAAGCAGCGGCTTATTCCAAGCGCCCAGCTTCCGAAAAAATCAGCGCCGGCACCGATCAAAAA
TGAACAGCAATTTATGACGTTCGGTGAAAGTGAGCCTGAGCGGAAACTGCCTGAAAAAACGCCGGAGCCGTCTTACTCGC
CGATGAAGCTGAGTTCGGTCGTAAAAGAGCCGGCGCCGGTAACAGAAGAAGAGTTTCACCCAAATGAAGCGGATCATGAA
GTGCCGTCGGAAACCAGCATGCCGGAAATGGCTGCGCCTGTTTCTGATATTCCGGCGCCGGAAGAGGAAGCTGTCTCCGA
AGAAATACAGGAAGAAAGAGTTCCGGTCATGTATCCGATCGGCCAAATGCACGGGACATATATTTTAGCCCAAAACGAAA
ACGGCCTGTATATCATTGACCAGCATGCGGCCCAAGAGCGGATTAAATACGAATATTTCCGGGAAAAAGTCGGGCAGGTT
GAGCCTGAAGTGCAGGATATGATCGTGCCGCTCACCTTTCACTATGCGGCAAATGAAGCGCTTATCATTGAACAGCATCA
GCATGAGCTTGAAAGTGTAGGGGTATTTTTAGAAGCTTTCGGCACTAACAGCTATATCGTCCGCTGCCATCCGGCCTGGT
TTCCAAAAGGGGAAGAAGCTGAACTGATTGAAGAAATCATTCAGCAGGTGCTTGACGCCAAACAGATCGACATTAAAAAA
CTTCGGGAGGAAGCCGCCATAATGATGAGCTGCAAAGGCTCGATCAAAGCGAACCGTCATTTGCGCAACGATGAAATCAA
AGCGCTCTTGGACGATCTGCGCCGAACGGCAGACCCGTTCACATGCCCGCACGGCCGGCCGATCATTATTCACCATAGCA
CGTATGAGATGGAAAAGATGTTTAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(440-581)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-85)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9P1JH09

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

46.368

100

0.48