Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   R2573_RS12890 Genome accession   NZ_CP137014
Coordinates   2647374..2648126 (-) Length   250 a.a.
NCBI ID   WP_012118107.1    Uniprot ID   A7Z796
Organism   Bacillus velezensis strain S161     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2642374..2653126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2573_RS12865 (R2573_12865) mreC 2642810..2643673 (-) 864 WP_007408166.1 rod shape-determining protein MreC -
  R2573_RS12870 (R2573_12870) mreB 2643704..2644717 (-) 1014 WP_003152647.1 cell shape-determining protein MreB -
  R2573_RS12875 (R2573_12875) radC 2644809..2645504 (-) 696 WP_007408165.1 DNA repair protein RadC -
  R2573_RS12880 (R2573_12880) - 2645536..2646105 (-) 570 WP_032873810.1 nucleoside triphosphate pyrophosphatase -
  R2573_RS12885 (R2573_12885) - 2646246..2647247 (-) 1002 WP_032873809.1 SPOR domain-containing protein -
  R2573_RS12890 (R2573_12890) comC 2647374..2648126 (-) 753 WP_012118107.1 A24 family peptidase Machinery gene
  R2573_RS12895 (R2573_12895) - 2648266..2649558 (-) 1293 WP_032873806.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  R2573_RS12900 (R2573_12900) - 2649617..2652259 (-) 2643 WP_032873804.1 valine--tRNA ligase -
  R2573_RS12905 (R2573_12905) - 2652712..2652903 (+) 192 WP_007612879.1 hypothetical protein -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 27219.94 Da        Isoelectric Point: 9.4293

>NTDB_id=894288 R2573_RS12890 WP_012118107.1 2647374..2648126(-) (comC) [Bacillus velezensis strain S161]
MLLILFFLGLIFGSFFYTAACRIPLRISVISPRSACSFCRLPLSWGELVPVVSYILQRGRCRNCRAKLSVMYPAAECWTA
CLFTAAGIHFGFSKELLVALLFLSLLMIVTMTDLQYMLIPDKVLLFFLPLFIAGRMFSPLDSWYAGFAGAVCGFFLLVFI
MFVSKGGIGAGDVKLFGVIGLTLGVKLVLIAFFLSVMIGAVYGMCAAARGRLGKKQPFPFAPAISAGSALSYLYGEELFS
FYIKLASGGA

Nucleotide


Download         Length: 753 bp        

>NTDB_id=894288 R2573_RS12890 WP_012118107.1 2647374..2648126(-) (comC) [Bacillus velezensis strain S161]
GTGCTTTTGATTCTGTTTTTTCTCGGTTTGATTTTCGGTTCTTTTTTTTATACAGCAGCGTGCCGTATCCCGCTTCGAAT
CTCGGTTATTTCGCCGCGTTCAGCCTGTTCGTTTTGCCGCTTGCCGCTCTCCTGGGGGGAGCTTGTGCCCGTCGTTTCTT
ATATTCTGCAAAGAGGCAGATGCAGAAACTGCCGTGCAAAGCTGTCGGTTATGTATCCGGCGGCGGAATGCTGGACGGCG
TGTTTATTCACGGCTGCAGGCATTCATTTCGGTTTCTCAAAAGAACTGTTAGTCGCGCTGTTATTTCTGTCTCTGCTCAT
GATTGTTACTATGACGGATCTGCAATATATGCTGATTCCTGACAAAGTTCTGCTGTTTTTTCTTCCGCTTTTCATCGCCG
GCCGCATGTTTTCTCCGCTGGATTCATGGTATGCAGGGTTTGCCGGAGCCGTTTGCGGATTTTTTCTGCTTGTTTTTATC
ATGTTTGTCAGTAAAGGAGGCATCGGCGCAGGTGATGTGAAACTGTTTGGGGTGATCGGCCTGACGCTCGGCGTGAAGCT
CGTGCTCATTGCATTCTTTCTTTCCGTTATGATCGGAGCCGTATACGGCATGTGCGCCGCAGCCCGGGGCAGGCTTGGTA
AAAAGCAGCCATTTCCGTTTGCGCCGGCCATCTCAGCCGGGAGCGCTTTGAGTTATTTATACGGTGAAGAGCTGTTTTCG
TTTTACATCAAGCTCGCTTCAGGCGGAGCTTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)

Type IV leader peptidase family (Peptidase_A24)

(101-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7Z796

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Bacillus subtilis subsp. subtilis str. 168

58.871

99.2

0.584