Detailed information NTG0894146

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: AAYT23_RS09485
• Genome accession: NZ_CP154877
• Coordinates: 1826846..1829380 (-)
• Length: 844 a.a.
• NCBI ID: WP_000963681.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20234295
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1821846..1834380

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT23_RS09470 (AAYT23_09455)	patB	1822448..1824214 (-)	1767	WP_000859859.1	multidrug efflux ABC transporter subunit PatB	-
AAYT23_RS09475 (AAYT23_09460)	-	1824406..1824753 (+)	348	Protein_1823	IS110 family transposase	-
AAYT23_RS09480 (AAYT23_09465)	patA	1825005..1826699 (-)	1695	WP_000908141.1	multidrug efflux ABC transporter subunit PatA	-
AAYT23_RS09485 (AAYT23_09470)	hexA	1826846..1829380 (-)	2535	WP_000963681.1	DNA mismatch repair protein MutS	Machinery gene
AAYT23_RS09490 (AAYT23_09475)	argR	1829431..1829877 (-)	447	WP_001231473.1	arginine repressor	-
AAYT23_RS09495 (AAYT23_09480)	argS	1830013..1831704 (+)	1692	WP_001092738.1	arginine--tRNA ligase	-
AAYT23_RS09500 (AAYT23_09485)	-	1832019..1832576 (-)	558	Protein_1828	transposase family protein	-
AAYT23_RS09505 (AAYT23_09490)	-	1832562..1833047 (+)	486	WP_001826677.1	cupin domain-containing protein	-
AAYT23_RS09510 (AAYT23_09495)	-	1833131..1833838 (+)	708	WP_000166475.1	response regulator transcription factor	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94878.39 Da
• Isoelectric Point: 4.9494

>NTDB_id=894146 AAYT23_RS09485 WP_000963681.1 1826846..1829380(-) (hexA) [Streptococcus pneumoniae strain 20234295]
MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQTASSKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELESLISAAIAP
EAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVGKYIQRLQTLAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSQIDIRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLQHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQTSA
VTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=894146 AAYT23_RS09485 WP_000963681.1 1826846..1829380(-) (hexA) [Streptococcus pneumoniae strain 20234295]
ATGGCGATAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGGATGGGTGATTTTTATGAATTATTTTATGAGGATGCGGTCAATGCTGCGCAGATTCTGGAAATTTCCTTAACGAGTC
GCAACAAGAATGCCGACAATCCGATCCCTATGGCGGGTGTTCCCTATCATTCTGCCCAACAGTATATCGATGTCTTGATT
GAGCAGGGTTATAAGGTGGCTATCGCAGAGCAGATGGAAGATCCTAAACAAGCAGTTGGGGTTGTTAAACGAGAGGTTGT
TCAGGTCATTACGCCAGGGACAGTGGTCGATAGCAGTAAGCCGGACAGTCAGAATAATTTTTTGGTTTCCATAGACCGCG
AAGGCAATCAATTTGGCCTAGCTTATATGGATTTGGTGACGGGTGACTTTTATGTGACAGGTCTTTTGGATTTCACGCTG
GTTTGTGGGGAAATCCGTAACCTCAAGGCTCGAGAAGTGGTGTTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATCCT
CAGCCGCCAGATGAATCTGGTACTCTCTTATGAAAAAGAAAGCTTTGAAGACCTTCATTTATTGGATTTGCGATTGGCAA
CGGTGGAGCAAACGGCATCTAGTAAGCTGCTCCAGTATGTTCATCGGACTCAGATGAGGGAATTGAACCACCTCAAACCT
GTTATCCGCTACGAAATTAAGGATTTCTTGCAGATGGATTATGCGACCAAGGCTAGTCTGGATTTGGTTGAGAATGCTCG
CTCAGGTAAGAAACAAGGCAGTCTTTTCTGGCTTTTGGATGAAACCAAAACGGCTATGGGGATGCGTCTCTTGCGTTCTT
GGATTCATCGCCCCTTGATTGATAAGGAACGAATCGTCCAACGTCAAGAAGTAGTGCAGGTCTTTCTCGACCATTTCTTT
GAGCGTAGTGACTTGACAGACAGTCTCAAGGGTGTTTATGACATTGAGCGCTTGGCTAGTCGTGTTTCTTTTGGCAAAAC
CAATCCAAAGGATCTCTTGCAGTTGGCGACTACCTTGTCTAGTGTGCCACGGATTCGTGCGATTTTAGAAGGGATGGAGC
AACCTACTCTAGCCTATCTCATCGCACAACTGGATGCAATCCCTGAGTTGGAGAGTTTGATTAGCGCAGCGATTGCTCCT
GAAGCTCCTCATGTGATTACAGATGGGGGAATTATCCGGACTGGATTTGATGAGACTTTAGACAAGTATCGTTGCGTTCT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGCGAGAAAACTCTGGTATCAGCACGCTCAAGATTGACT
ACAATAAAAAGGATGGCTACTATTTTCATGTGACCAATTCGCAACTAGGAAATGTGCCAGCCCACTTTTTTCGCAAGGCG
ACGCTGAAAAACTCAGAACGCTTTGGAACCGAAGAATTAGCCCGTATCGAGGGAGATATGCTTGAGGCGCGTGAGAAGTC
AGCCAACCTCGAATACGAAATATTTATGCGCATTCGTGAAGAGGTCGGCAAGTACATCCAGCGTTTACAAACTCTAGCCC
AAGGAATTGCGACGGTTGATGTCTTACAGAGTCTGGCGGTTGTGGCTGAAACCCAGCATTTGATTCGACCTGAGTTTGGT
GACGATTCACAAATTGATATCCGGAAAGGGCGCCATGCTGTCGTTGAAAAGGTTATGGGGGCTCAGACCTATATTCCAAA
TACGATTCAGATGGCAGAAGATACCAGTATTCAACTGGTTACAGGGCCAAACATGAGTGGGAAGTCTACCTATATGCGTC
AGTTAGCCATGACGGCGGTTATGGCCCAGCTGGGTTCCTATGTTCCTGCTGAAAGCGCCCATTTACCGATTTTTGATGCG
ATTTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCGGGTCAGTCAACCTTTATGGTGGAGATGATGGAGGCCAATAA
TGCCATTTCGCATGCGACCAAGAACTCTCTCATTCTCTTTGATGAATTGGGACGTGGAACTGCAACTTATGACGGGATGG
CTCTTGCTCAGTCCATCATCGAATATATCCATGAGCACATCGGAGCTAAGACCCTCTTTGCGACCCACTACCATGAGTTG
ACTAGTCTGGAGTCTAGTTTACAACACTTGGTCAATGTCCACGTGGCAACTTTGGAGCAGGATGGGCAGGTCACCTTCCT
TCACAAGATTGAACCGGGACCAGCTGATAAATCCTACGGTATCCATGTTGCCAAGATTGCTGGCTTGCCAGCAGACCTTT
TAGCAAGGGCGGATAAGATTTTGACTCAGCTAGAGAATCAAGGAACAGAGAGTCCTCCTCCCATGAGACAAACTAGTGCT
GTCACTGAACAGATTTCACTCTTTGATAGGGCAGAAGAGCATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTATAA
TATGACACCTATGCAGGTTATGAATGTCTTAGTAGAGTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	99.882	100	0.999
mutS	Pseudomonas stutzeri strain ATCC 17587	36.417	100	0.368