Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   AAYT23_RS05170 Genome accession   NZ_CP154877
Coordinates   1024053..1024517 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 20234295     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1019053..1029517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT23_RS05150 (AAYT23_05130) - 1020004..1020972 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  AAYT23_RS05155 (AAYT23_05135) pdrM 1021126..1022487 (-) 1362 WP_000278534.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  AAYT23_RS05160 (AAYT23_05140) - 1022498..1022758 (-) 261 WP_001105925.1 hypothetical protein -
  AAYT23_RS05165 (AAYT23_05145) - 1022772..1024040 (-) 1269 WP_000924489.1 dihydroorotase -
  AAYT23_RS05170 (AAYT23_05150) mutX 1024053..1024517 (-) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  AAYT23_RS05175 (AAYT23_05155) - 1024527..1025180 (-) 654 WP_000401329.1 uracil-DNA glycosylase -
  AAYT23_RS05180 (AAYT23_05160) - 1025318..1025569 (-) 252 Protein_1021 hypothetical protein -
  AAYT23_RS05185 (AAYT23_05165) - 1025760..1027106 (-) 1347 WP_001813192.1 IS1380-like element ISSpn5 family transposase -
  AAYT23_RS05190 (AAYT23_05170) - 1027687..1028400 (-) 714 WP_000499437.1 YjjG family noncanonical pyrimidine nucleotidase -
  AAYT23_RS05195 (AAYT23_05175) - 1028890..1028997 (-) 108 Protein_1024 hypothetical protein -
  AAYT23_RS05200 (AAYT23_05180) - 1028997..1029071 (-) 75 Protein_1025 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=894090 AAYT23_RS05170 WP_001135768.1 1024053..1024517(-) (mutX) [Streptococcus pneumoniae strain 20234295]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=894090 AAYT23_RS05170 WP_001135768.1 1024053..1024517(-) (mutX) [Streptococcus pneumoniae strain 20234295]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987