Detailed information NTG0894021

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: R0Q54_RS02280
• Genome accession: NZ_CP136992
• Coordinates: 388124..390454 (-)
• Length: 776 a.a.
• NCBI ID: WP_046160607.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain J46
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 383124..395454

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R0Q54_RS02245 (R0Q54_02245)	yqxA	383462..383800 (-)	339	WP_046160606.1	YqxA family protein	-
R0Q54_RS02250 (R0Q54_02250)	spoIIP	383817..385022 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
R0Q54_RS02255 (R0Q54_02255)	gpr	385085..386191 (-)	1107	WP_014480309.1	GPR endopeptidase	-
R0Q54_RS02260 (R0Q54_02260)	rpsT	386395..386661 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
R0Q54_RS02265 (R0Q54_02265)	holA	386676..387719 (-)	1044	WP_029317888.1	DNA polymerase III subunit delta	-
R0Q54_RS02270 (R0Q54_02270)	-	387759..387872 (-)	114	WP_122060479.1	hypothetical protein	-
R0Q54_RS02275 (R0Q54_02275)	yqzM	387949..388083 (+)	135	WP_003229983.1	YqzM family protein	-
R0Q54_RS02280 (R0Q54_02280)	comEC	388124..390454 (-)	2331	WP_046160607.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
R0Q54_RS02285 (R0Q54_02285)	comEB	390458..391027 (-)	570	WP_003229978.1	ComE operon protein 2	-
R0Q54_RS02290 (R0Q54_02290)	comEA	391094..391711 (-)	618	WP_046160608.1	competence protein ComEA	Machinery gene
R0Q54_RS02295 (R0Q54_02295)	comER	391795..392616 (+)	822	WP_032726195.1	late competence protein ComER	-
R0Q54_RS02300 (R0Q54_02300)	yqeM	392682..393425 (-)	744	WP_046160609.1	class I SAM-dependent DNA methyltransferase	-
R0Q54_RS02305 (R0Q54_02305)	rsfS	393422..393778 (-)	357	WP_014480315.1	ribosome silencing factor	-
R0Q54_RS02310 (R0Q54_02310)	yqeK	393796..394356 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
R0Q54_RS02315 (R0Q54_02315)	nadD	394346..394915 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
R0Q54_RS02320 (R0Q54_02320)	yhbY	394927..395217 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86846.48 Da
• Isoelectric Point: 7.2477

>NTDB_id=894021 R0Q54_RS02280 WP_046160607.1 388124..390454(-) (comEC) [Bacillus subtilis strain J46]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVKTPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFHQVKTSLRQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVEVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAEILLKYHKVKRLVIPKGFVSEPKDEKVLQAAREEGVEIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=894021 R0Q54_RS02280 WP_046160607.1 388124..390454(-) (comEC) [Bacillus subtilis strain J46]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAATTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGGCAGGAATTGTACAGGCACTTACAGTCGGTGACAGAT
TTTATGTGGAGGACGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCGATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATCCGTCTTGGTATAACAAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGTCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCATCA
GGTTAAAACCTCTTTGAGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGAAGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGAGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAGCAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGATTCTGCTGAAGTATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGGCAGCCAGGGAAG
AGGGAGTGGAAATTGAAGAGGTGAAGCGAGGCGATGTGTTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCGGAA
GCACCTGATCCGGCAAGCAAAAATAATTCATCTCTCGTTCTTTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAAGAGGTGATGAACGTGTTTCCGAATATAAAAGCAGATGTGTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGACCAAAA
CGGAACGATCCAATATAGATATAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.711	100	0.987