Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   R3H61_RS06860 Genome accession   NZ_CP136951
Coordinates   1390788..1391498 (-) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Spyo09     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1385788..1396498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R3H61_RS06845 (R3H61_06850) rnc 1387495..1388187 (-) 693 WP_011284596.1 ribonuclease III -
  R3H61_RS06850 (R3H61_06855) vicX 1388630..1389439 (-) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  R3H61_RS06855 (R3H61_06860) vicK 1389443..1390795 (-) 1353 WP_002990673.1 cell wall metabolism sensor histidine kinase VicK Regulator
  R3H61_RS06860 (R3H61_06865) vicR 1390788..1391498 (-) 711 WP_002985645.1 response regulator YycF Regulator
  R3H61_RS06865 (R3H61_06870) - 1391660..1392694 (-) 1035 WP_161761900.1 DUF3114 domain-containing protein -
  R3H61_RS06870 (R3H61_06875) - 1392750..1393997 (-) 1248 WP_014407393.1 AMP-binding protein -
  R3H61_RS06875 (R3H61_06880) - 1393954..1395102 (-) 1149 WP_129284138.1 acetyl-CoA C-acyltransferase -
  R3H61_RS06880 (R3H61_06885) - 1395497..1395646 (-) 150 WP_002990686.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=893727 R3H61_RS06860 WP_002985645.1 1390788..1391498(-) (vicR) [Streptococcus pyogenes strain Spyo09]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=893727 R3H61_RS06860 WP_002985645.1 1390788..1391498(-) (vicR) [Streptococcus pyogenes strain Spyo09]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCGCGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAAACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ATACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364