Detailed information
Overview
| Name | comS | Type | Regulator |
| Locus tag | R3H37_RS00340 | Genome accession | NZ_CP136948 |
| Coordinates | 55342..55440 (+) | Length | 32 a.a. |
| NCBI ID | WP_020833188.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain Spyo01 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| IS/Tn | 53962..55152 | 55342..55440 | flank | 190 |
Gene organization within MGE regions
Location: 53962..55440
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| R3H37_RS00335 (R3H37_00335) | - | 53962..55152 (-) | 1191 | WP_002299749.1 | IS256-like element ISLgar5 family transposase | - |
| R3H37_RS00340 (R3H37_00340) | comS | 55342..55440 (+) | 99 | WP_020833188.1 | quorum-sensing system DWW-type pheromone | Regulator |
Sequence
Protein
Download Length: 32 a.a. Molecular weight: 3758.63 Da Isoelectric Point: 10.7919
>NTDB_id=893577 R3H37_RS00340 WP_020833188.1 55342..55440(+) (comS) [Streptococcus pyogenes strain Spyo01]
MLKKVKPFLLLAAVVAFKVARVMHEFDWWNLG
MLKKVKPFLLLAAVVAFKVARVMHEFDWWNLG
Nucleotide
Download Length: 99 bp
>NTDB_id=893577 R3H37_RS00340 WP_020833188.1 55342..55440(+) (comS) [Streptococcus pyogenes strain Spyo01]
ATGTTAAAAAAAGTTAAGCCATTTTTACTATTAGCCGCAGTAGTTGCATTTAAAGTTGCTCGTGTAATGCATGAATTTGA
TTGGTGGAATCTTGGTTAA
ATGTTAAAAAAAGTTAAGCCATTTTTACTATTAGCCGCAGTAGTTGCATTTAAAGTTGCTCGTGTAATGCATGAATTTGA
TTGGTGGAATCTTGGTTAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comS | Streptococcus pyogenes MGAS315 |
100 |
100 |
1 |
| comS | Streptococcus pyogenes MGAS8232 |
45.161 |
96.875 |
0.437 |