Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   R3H37_RS00340 Genome accession   NZ_CP136948
Coordinates   55342..55440 (+) Length   32 a.a.
NCBI ID   WP_020833188.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Spyo01     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 53962..55152 55342..55440 flank 190


Gene organization within MGE regions


Location: 53962..55440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R3H37_RS00335 (R3H37_00335) - 53962..55152 (-) 1191 WP_002299749.1 IS256-like element ISLgar5 family transposase -
  R3H37_RS00340 (R3H37_00340) comS 55342..55440 (+) 99 WP_020833188.1 quorum-sensing system DWW-type pheromone Regulator

Sequence


Protein


Download         Length: 32 a.a.        Molecular weight: 3758.63 Da        Isoelectric Point: 10.7919

>NTDB_id=893577 R3H37_RS00340 WP_020833188.1 55342..55440(+) (comS) [Streptococcus pyogenes strain Spyo01]
MLKKVKPFLLLAAVVAFKVARVMHEFDWWNLG

Nucleotide


Download         Length: 99 bp        

>NTDB_id=893577 R3H37_RS00340 WP_020833188.1 55342..55440(+) (comS) [Streptococcus pyogenes strain Spyo01]
ATGTTAAAAAAAGTTAAGCCATTTTTACTATTAGCCGCAGTAGTTGCATTTAAAGTTGCTCGTGTAATGCATGAATTTGA
TTGGTGGAATCTTGGTTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

100

100

1

  comS Streptococcus pyogenes MGAS8232

45.161

96.875

0.437