Detailed information NTG0893574

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: RJD36_RS12300
• Genome accession: NZ_CP136943
• Coordinates: 2428702..2429967 (+)
• Length: 421 a.a.
• NCBI ID: WP_013852370.1
• Uniprot ID: A0AAE6YQ67
• Organism: Streptococcus pasteurianus strain WUSP082
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2423702..2434967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJD36_RS12270 (RJD36_12270)	-	2424169..2426763 (+)	2595	WP_048791414.1	YfhO family protein	-
RJD36_RS12615	-	2427196..2427624 (+)	429	Protein_2370	helix-turn-helix domain-containing protein	-
RJD36_RS12295 (RJD36_12295)	rlmH	2428012..2428491 (-)	480	WP_003067023.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
RJD36_RS12300 (RJD36_12300)	htrA	2428702..2429967 (+)	1266	WP_013852370.1	S1C family serine protease	Regulator
RJD36_RS12305 (RJD36_12305)	spo0J	2430027..2430803 (+)	777	WP_003067028.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 43814.70 Da
• Isoelectric Point: 4.1803

>NTDB_id=893574 RJD36_RS12300 WP_013852370.1 2428702..2429967(+) (htrA) [Streptococcus pasteurianus strain WUSP082]
MKKIKLPKLPKLPKFNYKNWLKPLGVILVGFIAGIAGTILVLNMAGISITNVSGSSTKTTTSSVSYSNSNDTTKAVEKVQ
DAVVSVINYKSDSSSSASDLYNQMFGNDSDSSSNSSSTDDLTVYSEGSGVIYKKDGDSAYVVTNNHVIDGAEQIEIMLAN
GTKVVGELVGADTYSDIAVVKISSDNVSTVAEFADSDKLTVGETAIAIGSPLGTEYANSVTQGIVSSLSRTVTMTNDDGE
TISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKISSTSSSGESVEGMGFAIPSNDVVSIINQLEENGQVIRPALGIS
MINLSDLSTNAIAQLNIPTSVTSGVVVAAVQSGMPAEGNLEQYDVITAIDDKEVTSTSDLQSILYTHSVGDSVKVTFYRG
TDKKTATIELTKTTQDLSSSN

Nucleotide

• Length: 1266 bp

>NTDB_id=893574 RJD36_RS12300 WP_013852370.1 2428702..2429967(+) (htrA) [Streptococcus pasteurianus strain WUSP082]
GTGAAAAAAATAAAATTACCAAAATTACCCAAGTTACCAAAATTTAATTACAAAAATTGGTTAAAACCATTGGGTGTCAT
TTTAGTCGGCTTTATAGCTGGTATCGCAGGTACAATACTCGTCCTAAACATGGCAGGTATTTCAATCACTAACGTCAGTG
GTTCAAGTACAAAAACAACAACAAGTAGCGTAAGCTATTCTAACTCTAACGATACAACAAAAGCTGTGGAAAAAGTTCAA
GACGCGGTTGTATCTGTTATTAACTACAAATCAGACTCGTCATCTTCTGCAAGTGACCTCTACAATCAAATGTTTGGCAA
TGACTCAGACAGTAGTAGCAATTCAAGCTCTACAGATGATTTGACTGTTTACAGTGAGGGGTCTGGGGTTATTTACAAAA
AAGATGGTGATTCTGCCTATGTCGTCACTAACAATCACGTTATTGATGGTGCCGAACAAATTGAAATTATGCTTGCTAAT
GGAACAAAAGTTGTTGGTGAGCTAGTCGGAGCAGATACTTATTCAGATATTGCTGTTGTTAAAATTTCTTCTGACAATGT
ATCTACAGTTGCTGAATTTGCCGATTCTGATAAATTGACTGTCGGTGAAACTGCTATCGCTATTGGTAGCCCACTTGGTA
CTGAATATGCTAACTCTGTAACACAAGGTATTGTCTCAAGTCTTAGCCGTACAGTAACCATGACAAATGATGATGGTGAA
ACTATCTCAACAAATGCTATCCAAACAGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCTTTAATTAACATTGAAGG
ACAAGTTATCGGTATCAATTCAAGTAAGATTTCATCTACATCAAGTTCTGGTGAATCTGTCGAAGGTATGGGATTTGCCA
TTCCATCTAACGATGTTGTATCCATTATTAACCAATTGGAAGAAAATGGGCAAGTTATCCGCCCAGCACTTGGTATTTCA
ATGATAAACTTGAGCGACCTTTCAACTAATGCAATTGCTCAACTTAACATTCCAACAAGTGTAACAAGCGGTGTCGTTGT
TGCCGCTGTTCAATCTGGTATGCCTGCTGAAGGTAATCTCGAACAGTACGATGTCATCACAGCTATTGACGACAAAGAAG
TAACATCTACTTCAGATCTTCAAAGTATTCTTTATACTCATTCTGTTGGTGACTCTGTCAAAGTAACCTTCTACCGTGGA
ACTGATAAGAAAACAGCTACAATTGAATTAACTAAGACAACGCAAGATTTATCTTCCTCAAACTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (315-410)

• Trypsin-like peptidase domain (Trypsin_2) (127-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	64.938	96.2	0.625
htrA	Streptococcus gordonii str. Challis substr. CH1	59.804	96.912	0.58
htrA	Streptococcus pneumoniae D39	57.664	97.625	0.563
htrA	Streptococcus pneumoniae TIGR4	57.664	97.625	0.563
htrA	Streptococcus mitis NCTC 12261	57.664	97.625	0.563
htrA	Streptococcus pneumoniae R6	57.664	97.625	0.563
htrA	Streptococcus pneumoniae Rx1	57.664	97.625	0.563